The visual message conveyed by retinal neurons to the brain when signaling natural scenes resembles the individual receptive fields only when viewed in context of the neuronal population.
Endocannabinoid activation of the CB1 receptor on retinal ganglion cells in the eye results in enhanced excitability and responsiveness to visual stimulation through a novel mechanism involving intracellular chloride regulation.
Genetic deletion of one Ptprb allele leads to increased phosphorylation of the TEK receptor, increasing Schlemm's canal area and protecting retinal ganglion cells in a mouse model of glaucoma.
Experimental and computational models reveal how parallel 'core' mechanisms shape direction selectivity at the dendrites of starburst amacrine cells and ganglion cells in the mouse retina.
A subset of retinal ganglion cells respond specifically to small moving objects and project to a visual area that plays a key role in prey capture behavior.
Multi-electrode recordings and modeling are combined to reveal the transformations of signals from cones to bipolar cells and then to ganglion cells within the primate retina.
The conductance-based encoding model creates a new bridge between statistical models and biophysical models of neurons, and infers visually-evoked excitatory and inhibitory synaptic conductances from spike trains in macaque retina.
Transsynaptic viral tracing reveals that neurons in the superior colliculus employ projection specific rules to the sampling of retinal inputs, directing distinct visual features to different downstream targets.
The mouse visual system is able to detect small moving objects due to the activity of VG3-amacrine cells, an unusual type of modulatory cell that uses the transmitter glutamate to activate retinal output cells.