411 results found
    1. Structural Biology and Molecular Biophysics
    2. Immunology and Inflammation

    Serum amyloid A is a retinol binding protein that transports retinol during bacterial infection

    Mehabaw G Derebe et al.
    Serum amyloid A proteins bind retinol with nanomolar affinity, and do so by forming oligomers that create a hydrophobic pocket that shields retinol from the aqueous environment.
    1. Structural Biology and Molecular Biophysics
    2. Immunology and Inflammation

    Immune Response: An ambulance for retinol

    Stephanie C Ganal, Andrew J MacPherson
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    1. Neuroscience

    The β-alanine transporter BalaT is required for visual neurotransmission in Drosophila

    Yongchao Han et al.
    BalaT-dependent β-alanine trafficking pathway in retinal pigment cells is critical for maintaining synaptic transmission of photoreceptor neurons in Drosophila.
    1. Computational and Systems Biology
    2. Physics of Living Systems

    Imaging single-cell blood flow in the smallest to largest vessels in the living retina

    Aby Joseph et al.
    By using a specialized camera that corrects for eye blur, millions of single-blood-cells are imaged, and their speed measured, as they travel through the largest-to-smallest vessels of the retina.
    1. Neuroscience

    LKB1 coordinates neurite remodeling to drive synapse layer emergence in the outer retina

    Courtney A Burger et al.
    LKB1 instructs the timing and location of synapse layer emergence in the outer retina by coordinating the regulation of pre- and postsynaptic neuron maturation and transport of synapse-associated proteins.
    1. Computational and Systems Biology
    2. Neuroscience

    Contrast sensitivity reveals an oculomotor strategy for temporally encoding space

    Antonino Casile et al.
    Fixational eye movements transform the spatial scene into temporal modulations on the retina, which, together with the known sensitivities of retinal neurons, provide a comprehensive account of human spatial sensitivity.
    1. Structural Biology and Molecular Biophysics

    Intraflagellar Transport: Moving proteins along in the cilium

    Narcis Adrian Petriman, Esben Lorentzen
    The structures of the bovine and human BBSome reveal that a conformational change is required to recruit the complex to the ciliary membrane.
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    1. Neuroscience

    Vision: Framing orientation selectivity

    Floris P de Lange, Matthias Ekman
    The ongoing debate on the neural basis of orientation selectivity in the primary visual cortex continues.
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    1. Neuroscience

    Visual Behavior: The eyes have it

    Mehmet Keleş, Mark A Frye
    Molecular genetic experiments are revealing how the fly brain generates behavioral responses to visual stimuli.
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    1. Medicine
    2. Stem Cells and Regenerative Medicine

    Tissue Engineering: Building a better model of the retina

    Milica Radisic
    Researchers have combined organ-on-a-chip engineering with the benefits of organoids to make improved models of the human retina.
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