Browse the search results

Page 2 of 20
    1. Plant Biology

    Regulation of rice root development by a retrotransposon acting as a microRNA sponge

    Jungnam Cho, Jerzy Paszkowski
    Retrotransposon-derived messenger RNA plays a critical role in rice root development via sequestration of miR171, which suggests a novel trans-acting regulation by transposable elements.
    1. Neuroscience

    Resolving rates of mutation in the brain using single-neuron genomics

    Gilad D Evrony, Eunjung Lee ... Christopher A Walsh
    The reanalysis of data from a recent study that claimed retrotransposon mutations are ubiquitous in the human brain outlines a general framework for the design and analysis of single-cell genomics studies.
    1. Developmental Biology
    2. Genetics and Genomics

    The GATOR complex regulates an essential response to meiotic double-stranded breaks in Drosophila

    Youheng Wei, Lucia Bettedi ... Mary A Lilly
    The GATOR complex regulates TORC1 activity during meiosis.
    1. Chromosomes and Gene Expression

    ZMYM2 controls human transposable element transcription through distinct co-regulatory complexes

    Danielle J Owen, Elisa Aguilar-Martinez ... Andrew D Sharrocks
    The transcriptional regulator ZMYM2 homes to distinct classes of retrotransposons bound by the TRIM28 and ChAHP chromatin complexes in human cells, which is broadly relevant in the transcriptional regulation field.
    1. Chromosomes and Gene Expression

    Artificially stimulating retrotransposon activity increases mortality and accelerates a subset of aging phenotypes in Drosophila

    Joyce Rigal, Ane Martin Anduaga ... Michael T Marr
    A genetic approach indicates that increased active somatic transposon activity can decrease life span and affect some but not all hallmarks of aging.
    1. Chromosomes and Gene Expression
    2. Evolutionary Biology

    Post-fertilization transcription initiation in an ancestral LTR retrotransposon drives lineage-specific genomic imprinting of ZDBF2

    Hisato Kobayashi, Tatsushi Igaki ... Kazuki Kurimoto
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    • Incomplete
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Evolution: A life LINE for large viruses

    Eugene V Koonin, Mart Krupovic
    As long suspected, poxviruses capture host genes through a reverse-transcription process now shown to be mediated by retrotransposons.
    Version of Record
    Insight
    1. Cell Biology
    2. Genetics and Genomics

    Retrotransposons: On the move

    Sandra L Martin
    The mechanisms by which a retrotransposon called LINE-1 duplicates itself and spreads through the human genome are becoming clearer.
    Version of Record
    Insight
    1. Genetics and Genomics

    Expression of most retrotransposons in human blood correlates with biological aging

    Yi-Ting Tsai, Nogayhan Seymen ... Mohammad M Karimi
    Despite no observed correlation between retrotransposon (RTE) activity and chronological age, the expression of most RTE classes and families except SINEs correlated with biological age-associated gene signature scores.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Condensation of LINE-1 is critical for retrotransposition

    Srinjoy Sil, Sarah Keegan ... Liam J Holt
    The LINE-1 retrotransposon protein, ORF1p, forms a condensate on RNA that is essential for retrotransposition, and may explain cis-preference through a co-translational assembly mechanism.