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    1. Neuroscience

    Rhythmic coordination of hippocampal neurons during associative memory processing

    Lara M Rangel, Jon W Rueckemann ... Howard Eichenbaum
    Different rhythms uniquely contribute to task-related processing in the hippocampus, and changes in the rhythmic profile of the hippocampus reflect dynamic coordination of its cell activity.
    1. Neuroscience

    On the normative advantages of dopamine and striatal opponency for learning and choice

    Alana Jaskir, Michael J Frank
    A computational model of the opponent neural architecture the basal ganglia, in tandem with adaptive dopamine modulation, exhibits robust advantages over traditional learning algorithms and ties together seemingly aberrant behavioral patterns resulting from dopamine and environmental manipulations across species.
    1. Neuroscience

    Activation of the dopaminergic pathway from VTA to the medial olfactory tubercle generates odor-preference and reward

    Zhijian Zhang, Qing Liu ... Fuqiang Xu
    The VTA-mOT DAergic pathway mediates a variety of naturalistic reward processes and different types of preferences including odor-preference.
    1. Neuroscience

    Interneuron-specific gamma synchronization indexes cue uncertainty and prediction errors in lateral prefrontal and anterior cingulate cortex

    Kianoush Banaie Boroujeni, Paul Tiesinga, Thilo Womelsdorf
    A fast spiking interneuron sub-type in medial and lateral prefrontal cortex fires and gamma-synchronizes prominently during adaptive learning of reward values when outcomes are uncertain and choice options have similar values.
    1. Neuroscience

    The rostral intralaminar nuclear complex of the thalamus supports striatally mediated action reinforcement

    Kara K Cover, Abby G Lieberman ... Brian N Mathur
    Neural circuit monitoring and manipulation reveal that neurons of the rostral intralaminar nuclei of the thalamus projecting to the dorsal striatum activate at movement initiation and reward to reinforce actions.
    1. Computational and Systems Biology
    2. Neuroscience

    An incentive circuit for memory dynamics in the mushroom body of Drosophila melanogaster

    Evripidis Gkanias, Li Yan McCurdy ... Barbara Webb
    Modelling differential roles for identified dopaminergic and output neurons of the fruit fly mushroom bodies, combined with a novel dopaminergic plasticity rule, explains neural and behavioural phenomena in olfactory learning tasks.
    1. Neuroscience

    Disruption of Nrxn1α within excitatory forebrain circuits drives value-based dysfunction

    Opeyemi O Alabi, M Felicia Davatolhagh ... Marc Vincent Fuccillo
    Disruption of the disease-associated synaptic adhesion molecule Neurexin1a in cortical excitatory neurons perturbs decision making and disrupts value-associated neural activity in downstream striatal circuits.
    1. Neuroscience

    Cell-type-specific responses to associative learning in the primary motor cortex

    Candice Lee, Emerson F Harkin ... Simon Chen
    Major neuronal subtypes in M1 show differential responses to reward and reward-associated stimuli and undergo cell-type-specific plasticity following associative learning.
    1. Neuroscience

    Reward-based training of recurrent neural networks for cognitive and value-based tasks

    H Francis Song, Guangyu R Yang, Xiao-Jing Wang
    A two-part neural network models reward-based training and provides a unified framework in which to study diverse computations that can be compared to electrophysiological recordings from behaving animals.
    1. Neuroscience

    Sensory perception drives food avoidance through excitatory basal forebrain circuits

    Jay M Patel, Jessica Swanson ... Benjamin R Arenkiel
    Glutamatergic projection neurons downstream of cholinergic cells in the basal forebrain potently affect feeding behavior by modulating downstream reward and aversion circuits.