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    1. Neuroscience

    Sensory prediction errors in the human midbrain signal identity violations independent of perceptual distance

    Javier A Suarez et al.
    Activity in the midbrain responds to unexpected changes in outcome identity (i.e. sensory prediction error) but does not scale with perceptual distance between expected and receipt reward.
    1. Neuroscience

    Two-photon imaging in mice shows striosomes and matrix have overlapping but differential reinforcement-related responses

    Bernard Bloem et al.
    Simultaneous 2-photon imaging of striosomes and matrix in mice shows that striosomes preferentially encode reward-predicting cues whereas both striatal compartments demonstrate reward-related activity.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Point of View: Is cell size a spandrel?

    Ariel Amir
    Analysis of experiments on bacteria suggests that the dependence of cell size on growth rate is not an adaptation but a causal consequence of a regulatory mechanism that controls DNA replication.
    1. Computational and Systems Biology
    2. Ecology

    Resource Competition: When communities collide

    Jason Merritt, Seppe Kuehn
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    1. Cell Biology

    Aging: A new answer to old questions

    Yves Barral
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    1. Neuroscience

    Neuroscience: Multitasking on the run

    Mary E Hatten, Stephen G Lisberger
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  1. Tutorial: How to draw the line in biomedical research

    Lisa Huang et al.
    When analysing the data in a two-dimensional scatter plot, researchers should consider plotting the three regression lines that can be calculated for such a plot.