5,389 results found
    1. Neuroscience

    The role of ventromedial prefrontal cortex in reward valuation and future thinking during intertemporal choice

    Elisa Ciaramelli et al.
    During decisions between smaller-immediate rewards and larger rewards available in the future, the ventromedial prefrontal cortex is critical to represent the value of rewards, not the future.
    1. Neuroscience

    Offline replay supports planning in human reinforcement learning

    Ida Momennejad et al.
    fMRI evidence for off-task replay predicts subsequent replanning behavior in humans, suggesting that learning from simulated experience during replay helps update past policies in reinforcement learning.
    1. Neuroscience

    Mediodorsal thalamus is required for discrete phases of goal-directed behavior in macaques

    Evan Wicker et al.
    Transient suppression of activity in the macaque mediodorsal thalamus impairs adjustment of secondary reinforcer values and disrupts appropriate action selection in a reinforcer devaluation task; this profile is distinct from that of amygdala or subregions of orbitofrontal cortex.
    1. Neuroscience

    A role for descending auditory cortical projections in songbird vocal learning

    Yael Mandelblat-Cerf et al.
    Midbrain dopaminergic neurons and a cortex-like structure called the arcopallium form part of a circuit that enables young songbirds to compare their own song with a template stored in memory, and use any discrepancies to improve their performance.
    1. Neuroscience

    Mesolimbic dopamine projections mediate cue-motivated reward seeking but not reward retrieval in rats

    Briac Halbout et al.
    Inhibiting ventral tegmental dopamine neurons, or their inputs to nucleus accumbens, disrupts cue-motivated reward seeking in a manner that depends on the microstructure of behavior.
    1. Neuroscience

    Rat behavior and dopamine release are modulated by conspecific distress

    Nina T Lichtenberg et al.
    Rat behavior and dopamine release are preferentially modulated by subjective rather than objective evaluation of outcomes in a social setting.
    1. Neuroscience

    Value signals guide abstraction during learning

    Aurelio Cortese et al.
    Valuation of sensory information in the ventromedial prefrontal cortex plays a key function in constructing the abstract representations that guide complex behaviours.
    1. Neuroscience

    Amphetamine reduces reward encoding and stabilizes neural dynamics in rat anterior cingulate cortex

    Saeedeh Hashemnia et al.
    Amphetamine reduces reward signaling by neurons in rat prefrontal cortex, but increases the stability of population dynamics, which account for animals’ increased task engagement, despite reduced reward motivation.
    1. Neuroscience

    The hippocampus encodes delay and value information during delay-discounting decision making

    Akira Masuda et al.
    Two distinct subpopulations of CA1 neurons that increased or decreased their firing rate during delay were identified, suggesting that they have distinct roles in the valuation process in the hippocampus.
    1. Neuroscience

    Functional heterogeneity within the rodent lateral orbitofrontal cortex dissociates outcome devaluation and reversal learning deficits

    Marios C Panayi, Simon Killcross
    The rodent orbitofrontal cortex makes functionally distinct contributions to flexible behavioural control, even within a single putative orbitofrontal subregion, which has important implications for establishing homology between rodent and primate orbitofrontal cortex.

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