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    1. Neuroscience

    Serotonergic neurons signal reward and punishment on multiple timescales

    Jeremiah Y Cohen et al.
    Serotonin-releasing neurons show tonic firing-rate changes correlating with global reward value in addition to phasic firing-rate changes correlating with local task events.
    1. Neuroscience

    Sequential neuromodulation of Hebbian plasticity offers mechanism for effective reward-based navigation

    Zuzanna Brzosko et al.
    Sequential neuromodulation by acetylcholine and dopamine enables correlational synaptic learning which, when incorporated into a computational model, yields effective navigation toward changing reward locations as in natural foraging behavior.
    1. Neuroscience

    Impaired voice processing in reward and salience circuits predicts social communication in children with autism

    Daniel Arthur Abrams et al.
    Children with autism often 'tune out' the voices in their environment and new results show that impaired processing of voices in the brain's reward system may underlie this social behavior.
    1. Neuroscience

    Impairments in laterodorsal tegmentum to VTA projections underlie glucocorticoid-triggered reward deficits

    Bárbara Coimbra et al.
    LDT-VTA dysfunction induced by prenatal glucocorticoid exposure leads to reward deficits that can be ameliorated by selective optogenetic activation of this circuit.
    1. Neuroscience

    Reward modulates the effect of visual cortical microstimulation on perceptual decisions

    Nela Cicmil et al.
    Evidence of an interaction between expected reward size and visual cortical microstimulation indicates that expected reward can affect sensory representations.
    1. Neuroscience

    Immediate perception of a reward is distinct from the reward’s long-term salience

    John P McGinnis et al.
    The experiences that are most rewarding at the time are not necessarily those that are remembered long-term.
    1. Neuroscience

    Reward prediction error does not explain movement selectivity in DMS-projecting dopamine neurons

    Rachel S Lee et al.
    Despite the fundamental relationship between movement and value, they are represented in a separable manner in dopamine neurons.
    1. Evolutionary Biology

    Long read sequencing reveals poxvirus evolution through rapid homogenization of gene arrays

    Thomas A Sasani et al.
    An adaptive process of genetic homogenization in poxviruses facilitates the propagation of single nucleotide variation within gene copies and might favor the persistence of large gene copy arrays.
    1. Chromosomes and Gene Expression
    2. Human Biology and Medicine

    Pervasive transcription read-through promotes aberrant expression of oncogenes and RNA chimeras in renal carcinoma

    Ana R Grosso et al.
    Transcription beyond annotated gene boundaries expands the diversity of the cancer transcriptome with overexpressed oncogenes and RNA chimeras.
    1. Neuroscience

    A nap to recap or how reward regulates hippocampal-prefrontal memory networks during daytime sleep in humans

    Kinga Igloi et al.
    Sleep plays a critical role in the selectivity of memory by promoting the retention of important memories at the expense of less relevant ones.