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    1. Developmental Biology
    2. Neuroscience

    A mutant with bilateral whisker to barrel inputs unveils somatosensory mapping rules in the cerebral cortex

    Nicolas Renier, Chloé Dominici ... Alain Chédotal
    The somatosensory cortex doesn't integrate mixed bilateral inputs, as partially uncrossing projections from the whiskers duplicates their representation by segregating lateralized inputs from each side of the head.
    1. Genetics and Genomics
    2. Neuroscience

    A single-cell transcriptomic and anatomic atlas of mouse dorsal raphe Pet1 neurons

    Benjamin W Okaty, Nikita Sturrock ... Susan M Dymecki
    Dorsal raphe Pet1 neurons are molecularly heterogeneous, comprising as many as fourteen distinct subtypes that show biased cell body distributions across dorsal raphe subdomains.
    1. Developmental Biology
    2. Neuroscience

    Olig3 regulates early cerebellar development

    Elijah D Lowenstein, Aleksandra Rusanova ... Luis R Hernandez-Miranda
    The transcription factor Olig3 safeguards the correct specification of early born cerebellar neuron derivatives and curtails an inhibitory interneuron differentiation program.
    1. Developmental Biology

    Bimodal function of chromatin remodeler Hmga1 in neural crest induction and Wnt-dependent emigration

    Shashank Gandhi, Erica J Hutchins ... Marianne E Bronner
    Chromatin remodeler Hmga1 has two separable functions in neural crest development, first neural crest specification at the neural plate border and later in Wnt-dependent emigration from the neural tube.
    1. Developmental Biology

    Fibrodysplasia ossificans progressiva mutant ACVR1 signals by multiple modalities in the developing zebrafish

    Robyn S Allen, Benjamin Tajer ... Mary C Mullins
    The human Fibrodysplasia-Ossificans-Progressiva BMP-receptor mutant signals in zebrafish in the absence of ligand-binding, displays BMP ligand-responsive hyperactivity, neither requiring other type-I-BMP receptors, unlike wild-type, challenging views of the pathological mechanism.
    1. Genetics and Genomics
    2. Medicine

    Impaired central pattern generators due to abnormal EPHA4 signaling leads to idiopathic scoliosis

    Lianlei Wang, Sen Zhao ... Nan Wu
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    • Incomplete
    1. Developmental Biology
    2. Neuroscience

    Embryonic Development: The evolution of hearing and balance

    Forrest P Weghorst, Karina S Cramer
    New genetic tools have allowed researchers to compare how the brainstem auditory and vestibular nuclei develop in embryonic chicks and mice.
    Version of Record
    Insight
    1. Neuroscience

    Molecular and anatomical organization of the dorsal raphe nucleus

    Kee Wui Huang, Nicole E Ochandarena ... Bernardo L Sabatini
    The dorsal raphe nucleus contains transcriptionally diverse cell classes that include subtypes of serotonergic neurons with distinct molecular and anatomical signatures.
    1. Neuroscience

    NOVA2-mediated RNA regulation is required for axonal pathfinding during development

    Yuhki Saito, Soledad Miranda-Rottmann ... Robert B Darnell
    The RNA-binding protein NOVA2 coordinately regulates the alternative splicing of key components in axon guidance and outgrowth pathways, with severe functional consequences.
    1. Developmental Biology
    2. Evolutionary Biology

    Bichir external gills arise via heterochronic shift that accelerates hyoid arch development

    Jan Stundl, Anna Pospisilova ... Robert Cerny
    Unique heterochrony in the cranial segments in bichirs triggers the early formation of their external gills, and might be informative about developmental mechanisms facilitating increased breathing capacity.