440 results found
    1. Cell Biology

    Bmal1 integrates mitochondrial metabolism and macrophage activation

    Ryan K Alexander et al.
    Macrophage Bmal1 controls the timing of the glycolytic to oxidative metabolism transition that dictates the extent of Hif-1a activation and the associated inflammatory response.
  1. Research Culture: A survey of travel behaviour among scientists in Germany and the potential for change

    Verena Haage
    A survey of scientists working in Germany reveals that most already travel to conferences in a sustainable manner and would be willing to make further changes to protect the environment.
    1. Neuroscience

    Mechanisms of competitive selection: A canonical neural circuit framework

    Shreesh P Mysore, Ninad B Kothari
    A first principles, neuro-computational framework proposes a path for the experimental dissection of neural circuit mechanisms of competitive selection across brain areas and animal species.
    1. Neuroscience

    Acetylcholine acts on songbird premotor circuitry to invigorate vocal output

    Paul I Jaffe, Michael S Brainard
    The neuromodulator acetylcholine contributes to state-dependent modulation of motor vigor and variability by direct action on songbird premotor cortex, bypassing basal ganglia circuitry.
    1. Neuroscience

    Alterations in the amplitude and burst rate of beta oscillations impair reward-dependent motor learning in anxiety

    Sebastian Sporn et al.
    State anxiety alters the dynamics of beta oscillations during reward-dependent motor learning, thereby impairing proper updating of motor predictions when learning in unstable environments.
    1. Cell Biology

    Single cell transcriptomics identifies a unique adipose lineage cell population that regulates bone marrow environment

    Leilei Zhong et al.
    A newly identified adipose lineage cell population, MALP, regulates marrow vasculature and osteogenesis in bone.
    1. Neuroscience

    Probabilistic, spinally-gated control of bladder pressure and autonomous micturition by Barrington’s nucleus CRH neurons

    Hiroki Ito et al.
    Ponto-spinal CRH neurons in Barrington’s nucleus are a core component of an inferential circuit that regulates autonomous micturition and generates voids when the bladder is full.
    1. Neuroscience

    Cre-assisted fine-mapping of neural circuits using orthogonal split inteins

    Haojiang Luan et al.
    A genetic method allows neurons to be individually identified and characterized by combining information about both their developmental origins and their mature patterns of gene expression.
    1. Neuroscience

    Low-frequency neural activity reflects rule-based chunking during speech listening

    Peiqing Jin et al.
    Neuroimaging reveals that the brain response to spoken language can be better explained by rule-based models than statistical models recently developed in artificial intelligence research.
    1. Developmental Biology
    2. Plant Biology

    Temporal integration of auxin information for the regulation of patterning

    Carlos S Galvan-Ampudia et al.
    Rhythmic centrifugal waves of auxin traveling through the tissue provides high definition positional information to cells that is not only spatial but also temporal.

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