97 results found
    1. Neuroscience

    The presynaptic ribbon maintains vesicle populations at the hair cell afferent fiber synapse

    Lars Becker et al.
    The auditory hair cell synaptic ribbon maintains vesicle pools near release sites in order to support sustained and timed vesicle release.
    1. Neuroscience

    Otoferlin acts as a Ca2+ sensor for vesicle fusion and vesicle pool replenishment at auditory hair cell ribbon synapses

    Nicolas Michalski et al.
    Targeted mutations in a Ca2+-binding site of otoferlin, a transmembrane protein of synaptic vesicles defective in a recessive form of deafness, reveal its Ca2+ sensor role both for vesicle fusion and vesicle pool replenishment.
    1. Neuroscience

    Neurotrophin-3 regulates ribbon synapse density in the cochlea and induces synapse regeneration after acoustic trauma

    Guoqiang Wan et al.
    Overexpression of the growth factor neurotrophin-3 helps to repair noise-induced damage in the mouse inner ear by promoting the regeneration of damaged synapses.
    1. Developmental Biology and Stem Cells
    2. Neuroscience

    A Gata3–Mafb transcriptional network directs post-synaptic differentiation in synapses specialized for hearing

    Wei-Ming Yu et al.
    Genetic studies in mice identify the transcription factor MafB as a potent regulator of specific features of the synapses underlying hearing.
    1. Cell Biology
    2. Neuroscience

    The synaptic ribbon is critical for sound encoding at high rates and with temporal precision

    Philippe Jean et al.
    The synaptic ribbon regulates calcium channel clustering and proper vesicle dynamics at cochlear inner hair cells to ensure precise sound encoding.
    1. Neuroscience

    Endocytosis: Recycling at synapses

    Owen P Gross, Henrique von Gersdorff
    Insight
    Available as:
    • HTML
    • PDF
    1. Neuroscience

    MEF2C regulates cortical inhibitory and excitatory synapses and behaviors relevant to neurodevelopmental disorders

    Adam J Harrington et al.
    Mice that lack the autism- and schizophrenia-linked gene MEF2C in cortical neurons have an imbalance of excitatory and inhibitory synapses, and impaired social and cognitive abilities.
    1. Neuroscience

    Organization and function of Drosophila odorant binding proteins

    Nikki K Larter et al.
    A genetic analysis reveals that some olfactory sensilla of Drosophila do not require an abundant odorant binding protein and that one such protein may act in gain control.
    1. Developmental Biology and Stem Cells
    2. Neuroscience

    Directional selectivity of afferent neurons in zebrafish neuromasts is regulated by Emx2 in presynaptic hair cells

    Young Rae Ji et al.
    Emx2 mediates the directional selectivity of neuromasts by regulating hair bundle orientation in hair cells, and by selecting afferent neuronal targets.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Live-cell mapping of organelle-associated RNAs via proximity biotinylation combined with protein-RNA crosslinking

    Pornchai Kaewsapsak et al.
    Live-cell nanometer-resolution RNA labeling method enables transcriptome-wide mapping of endogenous RNAs in nuclear, cytosol, ER, and mitochondrial subcompartments.

Refine your results by:

Type
Research categories