55 results found
    1. Microbiology and Infectious Disease

    Cyclic di-AMP drives developmental cycle progression in Chlamydia trachomatis

    Junghoon Lee, Scot P Ouellette
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    • Incomplete
    1. Chromosomes and Gene Expression
    2. Evolutionary Biology

    The emergence and evolution of gene expression in genome regions replete with regulatory motifs

    Timothy Fuqua, Yiqiao Sun, Andreas Wagner
    Mutagenizing sequences enriched with promoter motifs creates gene expression de novo, and helps to understand promoter logic, regulatory evolution, and the birth of de novo genes.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Ligand response of guanidine-IV riboswitch at single-molecule level

    Lingzhi Gao, Dian Chen, Yu Liu
    A folding-function model for the guanidine-IV riboswitch under both guanidine-free and guanidine-present conditions offers valuable insights into its regulatory mechanism.
    1. Evolutionary Biology

    Coenzyme-Protein Interactions since Early Life

    Alma Carolina Sanchez-Rocha, Mikhail Makarov ... Klára Hlouchová
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Microbiology and Infectious Disease

    A bacterial regulatory uORF senses multiple classes of ribosome-targeting antibiotics

    Gabriele Baniulyte, Joseph T Wade
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Biochemistry and Chemical Biology
    2. Plant Biology

    Guanidine production by plant homoarginine-6-hydroxylases

    Dietmar Funck, Malte Sinn ... Jörg S Hartig
    2-Oxoglutarate and Fe(II)-dependent dioxygenases from clade C23 are the major source of guanidine in plants and release guanidine from arginine or homoarginine by C5 or C6 hydroxylation, respectively.
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    A Vibrio cholerae viral satellite maximizes its spread and inhibits phage by remodeling hijacked phage coat proteins into small capsids

    Caroline M Boyd, Sundharraman Subramanian ... Kimberley D Seed
    A phage parasite encodes an external scaffolding protein to pirate and rearrange phage-encoded coat proteins to more efficiently transfer the phage parasite genome to new hosts and limit phage production.
    1. Cell Biology

    Global analysis of contact-dependent human-to-mouse intercellular mRNA and lncRNA transfer in cell culture

    Sandipan Dasgupta, Daniella Y Dayagi ... Jeffrey E Gerst
    The RNA transferome comprises full-length mRNAs and lncRNAs that undergo non-selective and expression-dependent transfer between mammalian cells in culture via actin-based tunneling nanotubes.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    RNA sequence to structure analysis from comprehensive pairwise mutagenesis of multiple self-cleaving ribozymes

    Jessica M Roberts, James D Beck ... Eric J Hayden
    A high-throughput analysis of several self-cleaving ribozymes reveals the effect of every possible mutation, and every possible pair of mutations, and how patterns in the relative activity data can be mapped to canonical and non-canonical structural elements.
    1. Microbiology and Infectious Disease

    Glutamine synthetase mRNA releases sRNA from its 3′UTR to regulate carbon/nitrogen metabolic balance in Enterobacteriaceae

    Masatoshi Miyakoshi, Teppei Morita ... Kan Tanaka
    Under nitrogen limitation, Salmonella and Escherichia coli express a messenger RNA to translate glutamine synthetase, and concomitantly the messenger RNA produces a small RNA from its 3′ end to inhibit the translation of 2-oxoglutarate dehydrogenase of the TCA cycle.

Refine your results by:

Type
Research categories