1,639 results found
    1. Microbiology and Infectious Disease

    Type I interferon underlies severe disease associated with Junín virus infection in mice

    Brady T Hickerson et al.
    The first lethal Junín virus challenge model in immunocompetent mice provides insight into New World mammarenavirus pathogenesis and will serve as a model for the development of much-needed therapeutic interventions.
    1. Microbiology and Infectious Disease

    Parvovirus minute virus of mice interacts with sites of cellular DNA damage to establish and amplify its lytic infection

    Kinjal Majumder et al.
    Development of a generally adaptable conformational capture assay for use in-trans identifies the specific direct interaction sites between the parvovirus minute virus of mice and the cellular genome during infection as sites of cellular DNA damage.
    1. Plant Biology

    A viral protein promotes host SAMS1 activity and ethylene production for the benefit of virus infection

    Shanshan Zhao et al.
    Rice dwarf virus Pns11 protein increases rice susceptibility to virus infection by enhancing OsSAMS1 enzymatic activity and ethylene production.
    1. Microbiology and Infectious Disease

    Mechanisms of virus dissemination in bone marrow of HIV-1–infected humanized BLT mice

    Mark S Ladinsky et al.
    Large-volume light microscopy combined with higher-resolution electron tomography revealed the spatial distribution of virus-producing cells and highlighted mechanisms of HIV-1 dissemination in bone marrow from a small animal model.
    1. Microbiology and Infectious Disease
    2. Plant Biology

    Viral-inducible Argonaute18 confers broad-spectrum virus resistance in rice by sequestering a host microRNA

    Jianguo Wu et al.
    The cooperative antiviral activity of two distinct AGO proteins could be exploited to provide a new strategy for controlling viral diseases in rice.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    RAGE deficiency predisposes mice to virus-induced paucigranulocytic asthma

    Jaisy Arikkatt et al.
    HMGB1 drives the development of paucigranulocytic asthma in RAGE deficient mice.
    1. Microbiology and Infectious Disease

    The c-Jun N-terminal kinase pathway of a vector insect is activated by virus capsid protein and promotes viral replication

    Wei Wang et al.
    Plant viruses enhance their replication in vector insects by activating the vector's JNK pathway, and inhibition of this pathway may be a useful strategy for controlling transmission of plant viruses.
    1. Microbiology and Infectious Disease

    Sexual transmission of murine papillomavirus (MmuPV1) in Mus musculus

    Megan E Spurgeon, Paul F Lambert
    MmuPV1, a papillomavirus that infects laboratory mice (Mus musculus), is discovered to be sexually transmitted, providing a new animal virus model to study sexually transmitted human papillomaviruses (HPVs).
    1. Microbiology and Infectious Disease

    The kinetoplastid-infecting Bodo saltans virus (BsV), a window into the most abundant giant viruses in the sea

    Christoph M Deeg et al.
    Bodo saltans virus defines the most abundant giant viruses in the ocean and highlights the genomic plasticity, rooted in evolutionary arms races, that gave rise to giant viruses.

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