4,435 results found
    1. Evolutionary Biology
    Paleontology

    Paleontology: A Collection of Articles

    Edited by Ian Baldwin et al.
    eLife has published papers on topics as diverse as paleoproteomics, ancient insects and the discovery of a new hominin species.
  1. Episode 48: June 2018

    In this episode, we hear about why we always have space for dessert, how collecting seeds from large areas could help restoration projects, gut bacteria, the placebo effect and toxoplasmosis.
    1. Microbiology and Infectious Disease

    Mechanistic Microbiome Studies: A Special Issue

    Edited by Wendy S Garrett et al.
    eLife is pleased to present a Special Issue to highlight recent advances in the mechanistic understanding of microbiome function.
  2. Episode 38: May 2017

    In this episode we hear about biofilms in bacteria, drug production, gender bias in peer review, nematode worms and how synchronising brain waves can boost memory.
  3. The cone snail Conus geographicus eating a goby fish

    Episode 55: March 2019

    In this episode, we hear about fast-acting insulin in cone snails, the roots of addiction, new gene editing techniques and gender biases in joint first authors.
    1. Medicine

    Loss of adaptive capacity in asthmatic patients revealed by biomarker fluctuation dynamics after rhinovirus challenge

    Anirban Sinha et al.
    Fluctuation of biomarkers is a novel way of studying system stability during stable and unstable states of health and disease, revealing the systems' ability to cope with external perturbations.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Positively selected modifications in the pore of TbAQP2 allow pentamidine to enter Trypanosoma brucei

    Ali H Alghamdi et al.
    Study of TbAQP2 adaptations and substrate interactions shows how this aquaglyceroporin enables cellular entry of large antimicrobial agents in Trypanosoma brucei.
    1. Ecology
    2. Evolutionary Biology

    Eco-evolutionary dynamics of nested Darwinian populations and the emergence of community-level heredity

    Guilhem Doulcier et al.
    Artificial selection on communities drives the evolution of interactions and establishes community-level inheritance.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Structural insights into the Ca2+-dependent gating of the human mitochondrial calcium uniporter

    Yan Wang et al.
    Cryo-EM structures of human MCU-EMRE-MICU1-MICU2 complex in the apo and Ca2+-bound states reveal how MICU1 and MICU2 impart their gating function to the mitochondrial calcium uniporter.
    1. Stem Cells and Regenerative Medicine

    Ecdysone steroid hormone remote controls intestinal stem cell fate decisions via the PPARγ-homolog Eip75B in Drosophila

    Lisa Zipper et al.
    A systemic hormone controls progenitor fate decisions independent of local fate determining pathways in the adult intestinal stem cell niche of Drosophila melanogaster..

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