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    1. Computational and Systems Biology
    2. Neuroscience

    Trading mental effort for confidence in the metacognitive control of value-based decision-making

    Douglas G Lee, Jean Daunizeau
    Intra-individual variability in choice, response time, subjective effort, confidence, and choice-induced preference change and certainty gain is explained by a cost–benefit model of cognitive resource allocation.
    1. Neuroscience

    Neural representation of abstract task structure during generalization

    Avinash R Vaidya, Henry M Jones ... David Badre
    The human brain maintains a representation of latent task states within frontoparietal networks during the generalization of behaviors to novel settings.
    1. Developmental Biology
    2. Neuroscience

    Cellular birthdate predicts laminar and regional cholinergic projection topography in the forebrain

    Kathryn C Allaway, William Muñoz ... Gordon Fishell
    Cholinergic populations with distinct cellular birthdates innervate deep versus superficial layers of the cortex with exquisite specificity.
    1. Developmental Biology

    A transient role of the ciliary gene Inpp5e in controlling direct versus indirect neurogenesis in cortical development

    Kerstin Hasenpusch-Theil, Christine Laclef ... Thomas Theil
    Primary-cilia-mediated processing of the Gli3 transcription factor enables the formation of subtypes of projection neurons in appropriate numbers during the development of the cerebral cortex.
    1. Neuroscience

    Modular output circuits of the fastigial nucleus for diverse motor and nonmotor functions of the cerebellar vermis

    Hirofumi Fujita, Takashi Kodama, Sascha du Lac
    Medial cerebellar nucleus comprises five major types of excitatory projection neurons differentially connected with specific subsets of inferior olive neurons, Purkinje cells, and somatomotor, oromotor, positional-autonomic, orienting and arousal circuits.
    1. Evolutionary Biology
    2. Neuroscience

    Mushroom body evolution demonstrates homology and divergence across Pancrustacea

    Nicholas James Strausfeld, Gabriella Hanna Wolff, Marcel Ethan Sayre
    Demonstrating extreme diversity across crustaceans while contrasting with evolutionary stability in insects, mushroom body homologues further underpin the unity of Pancrustacea and shed new light on arthropod brain evolution.
    1. Neuroscience

    Tonotopic and non-auditory organization of the mouse dorsal inferior colliculus revealed by two-photon imaging

    Aaron Benson Wong, J Gerard G Borst
    A spatial analysis of auditory and non-auditory properties of excitatory and inhibitory neurons in the mouse dorsal inferior colliculus defines the border between the lateral and the dorsal cortex.
    1. Neuroscience

    Anatomical and physiological foundations of cerebello-hippocampal interaction

    Thomas Charles Watson, Pauline Obiang ... Laure Rondi-Reig
    Anatomical tracing and physiological recordings reveal neuronal pathways through which the cerebellum may influence hippocampal activity.
    1. Neuroscience

    Computational mechanisms of curiosity and goal-directed exploration

    Philipp Schwartenbeck, Johannes Passecker ... Karl J Friston
    Distinct computational levels of uncertainty compel agents to gain information about hidden states in the world (‘active inference’) or optimise their ‘world model’ as such (‘active learning’).
    1. Neuroscience

    Human VMPFC encodes early signatures of confidence in perceptual decisions

    Sabina Gherman, Marios G. Philiastides
    Simultaneous EEG-fMRI reveals neural representations of decision confidence unfolding prior to explicit perceptual choices, in a region of the ventromedial prefrontal cortex typically linked to reward processing and value-based decisions.