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    1. Neuroscience

    Neurocalcin regulates nighttime sleep and arousal in Drosophila

    Ko-Fan Chen, Simon Lowe ... James Jepson
    The neuronal calcium sensor Neurocalcin regulates sleep and arousal thresholds during the night in Drosophila.
    1. Neuroscience

    Simultaneous brain, brainstem, and spinal cord pharmacological-fMRI reveals involvement of an endogenous opioid network in attentional analgesia

    Valeria Oliva, Ron Hartley-Davies ... Jonathan CW Brooks
    Attention-grabbing tasks produce rapid opioid-mediated analgesia via the descending pain modulation network to alter spinal neuronal activity.
    1. Chromosomes and Gene Expression
    2. Computational and Systems Biology

    Nanopore direct RNA sequencing maps the complexity of Arabidopsis mRNA processing and m6A modification

    Matthew T Parker, Katarzyna Knop ... Gordon G Simpson
    Sequencing mRNA directly with nanopores can reveal the authentic combinations of multiple mRNA processing events in full-length mRNA molecules in addition to identifying base modifications.
    1. Neuroscience

    Striatal fast-spiking interneurons selectively modulate circuit output and are required for habitual behavior

    Justin K O'Hare, Haofang Li ... Nicole Calakos
    Fast-spiking interneurons of the dorsolateral striatum are found to provide a microcircuit mechanism driving the circuit properties and behavioral adaptations that characterize habit.
    1. Neuroscience

    An Information-Theoretic Approach to Reward Rate Optimization in the Tradeoff Between Controlled and Automatic Processing in Neural Network Architectures

    Giovanni Petri, Sebastian Musslick, Jonathan D. Cohen
    Not revised
    Reviewed Preprint v1
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    • Incomplete
    1. Cell Biology

    Cytokinesis in vertebrate cells initiates by contraction of an equatorial actomyosin network composed of randomly oriented filaments

    Felix Spira, Sara Cuylen-Haering ... Daniel W Gerlich
    Asymmetric tension increase along the cell equator promotes self-organization of actomyosin into a partially aligned network during cytokinetic cleavage furrow ingression of vertebrate cells.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Vasohibin1, a new mouse cardiomyocyte IRES trans-acting factor that regulates translation in early hypoxia

    Fransky Hantelys, Anne-Claire Godet ... Anne-Catherine Prats
    In mouse cardiomyocytes, (lymph)angiogenic growth factors are induced during early hypoxia by a translational mechanism involving a new IRES trans-acting factor, vasohibin-1.
    1. Microbiology and Infectious Disease

    Human immunodeficiency virus-1 induces host genomic R-loops and preferentially integrates its genome near the R-loop regions

    Kiwon Park, Dohoon Lee ... Kwangseog Ahn
    Investigation of the role of triple-stranded nucleic acid, R-loops, in HIV-1 genome integration.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    A precisely adjustable, variation-suppressed eukaryotic transcriptional controller to enable genetic discovery

    Asli Azizoglu, Roger Brent, Fabian Rudolf
    A new gene expression tool enables precise control of protein dosage over a large range and paves the way for new genetic discoveries.
    1. Developmental Biology
    2. Neuroscience

    Receptor-specific interactome as a hub for rapid cue-induced selective translation in axons

    Max Koppers, Roberta Cagnetta ... Christine E Holt
    Multiple axonal guidance receptors control the local and selective translation of mRNAs by binding to ribosomes, specific mRNAs and RNA-binding proteins.
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