Salt-inducible kinase 3 (SIK3) is an essential component of the mammalian circadian clock machinery, which governs robust circadian behavioral and other rhythms by destabilization of a core clock protein PER2 in a phosphorylation-dependent manner.
A fish-derived bile salt was shown to act as interspecific infochemical, inducing the widespread predator avoidance behavior diel vertical migration at picomolar concentrations in freshwater zooplankton of the genus Daphnia.
The probability of a cellular response to a differentiation inducing signal is correlated with the dynamic expression of a Ras protein, and produces a ‘salt and pepper’ pattern of cell differentiation.
A functional link between representative family members of the CLCA channel regulator family and TMEM16 channels suggests that these protein families may cooperate in influencing multiple homeostatic and disease physiologies.
Stimuli are encoded differently in the brain when perceived consciously and unconsciously; for conscious perception, the representations are stronger in certain brain regions and they display more complex dynamics.