438 results found
  1. June 2015

    Episode 21: June 2015

    In this episode we hear about tinnitus and hyperacusis, salamanders, chemical harpoons, and the role of ultrasound and song in the mating rituals of mice and flies.
  2. Parents and children work together to build a tower of blocks that feature images representing work and family activities that a scientist may take part in

    Scientist and Parent

    Edited by Emma Pewsey et al.
    A research career and family life are not incompatible.
    1. Neuroscience

    Evolution of neuronal anatomy and circuitry in two highly divergent nematode species

    Ray L Hong et al.
    The substrate for evolutionary divergence does not lie in changes in neuronal cell number or targeting, but rather in sensory perception and synaptic partner choice within invariant, prepatterned neuronal processes.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Herpesviral lytic gene functions render the viral genome susceptible to novel editing by CRISPR/Cas9

    Hyung Suk Oh et al.
    CRISPR genome editing technology can efficiently introduce mutations into lytic and latent HSV genomes to block lytic replication and reactivation of latent herpes simplex virus genome though differential mechanisms.
    1. Chromosomes and Gene Expression
    2. Computational and Systems Biology

    Transcriptome maps of general eukaryotic RNA degradation factors

    Salma Sohrabi-Jahromi et al.
    Mapping of 30 general RNA degradation factors onto the yeast transcriptome provides the global distribution of factors for RNA turnover and surveillance in a eukaryotic cell.
    1. Developmental Biology
    2. Physics of Living Systems

    Cerebellar folding is initiated by mechanical constraints on a fluid-like layer without a cellular pre-pattern

    Andrew K Lawton et al.
    A multi-phase wrinkling model accounts for the radial and circumferential tension and differential expansion between a uniformly proliferating outer fluid-like layer and an incompressible core that together drive cerebellar folding.
    1. Developmental Biology
    2. Evolutionary Biology

    An integrative genomic analysis of the Longshanks selection experiment for longer limbs in mice

    João PL Castro et al.
    Genome sequencing of mice selected for longer limbs reveals that rapid selection response is due to both discrete loci and polygenic adaptation.
    1. Human Biology and Medicine
    2. Neuroscience

    Non-selective inhibition of inappropriate motor-tendencies during response-conflict by a fronto-subthalamic mechanism

    Jan R Wessel et al.
    Action-selection under response-conflict is buttressed by an inhibitory control signal from the basal ganglia that non-selectively suppresses motor excitability.
    1. Immunology and Inflammation

    HDAC3 restrains CD8-lineage genes to maintain a bi-potential state in CD4+CD8+ thymocytes for CD4-lineage commitment

    Rachael Laura Philips et al.
    CD4 lineage commitment requires HDAC3 to prevent premature upregulation of CD8 lineage genes during T cell development.
    1. Cell Biology

    Actin assembly ruptures the nuclear envelope by prying the lamina away from nuclear pores and nuclear membranes in starfish oocytes

    Natalia Wesolowska et al.
    Combined light and electron microscopy reveals a new function for Arp2/3-mediated actin assembly in nuclear envelope rupture, which leads to a separation of nuclear membranes and pores from the lamina.

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