A synthetic quadrastable gene network provides a synthetic biology framework to study cell fate determination.

One-quarter of the Chondrichthyes have an elevated risk of extinction, mainly as a result of overfishing.

Muscle power-generating capabilities, and not energetic limitations, limit the breaching abilities of the largest whales.

The chemokine CXCL13 is critical to the development of air pollution- and tobacco smoke-induced lung cancers.

Analysis of data on drug-gene interactions suggests that decentralized collaboration will increase the robustness of scientific findings in biomedical research.

The physical interaction network encoded in the multi-domain protein native structure handles the trade-off between the fast, stable folding and the efficient, reliable function.

The value of any choice is not static but dynamically changes as a function of the context of the alternatives even if they are seemingly irrelevant.

Integrated experimental-computational approaches were implemented to reveal the dynamic conformational landscape of a biologically relevant protein methyltransferase SETD8 for functional annotation.

Editors' Summary: This Replication Study has reproduced some parts of the original paper but other parts could not be interpreted.

Genomic associations with lifespan principally reflect heart disease/smoking/dementia but not other cancers, and distinguish lifespan differences of five years between top/bottom deciles of a score derived from DNA alone.