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    1. Cell Biology
    2. Computational and Systems Biology

    Science Forum: The Human Cell Atlas

    Aviv Regev, Sarah A Teichmann ... Human Cell Atlas Meeting Participants
    Advances in techniques for analysing single cells and tissues have inspired an international effort to create comprehensive reference maps of all human cells - the fundamental units of life - as a basis for both understanding human health and diagnosing, monitoring and treating disease.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Mapping influenza transmission in the ferret model to transmission in humans

    Michael G Buhnerkempe, Katelyn Gostic ... James O Lloyd-Smith
    Influenza transmission among ferrets correlates strongly with transmission among humans, so the ferret model for influenza transmission is a valid tool for pandemic potential in humans.
  1. Peer Review: Consultative review is worth the wait

    Stuart RF King
    Editors, reviewers and authors share their experiences of consultative peer review at eLife.
    1. Microbiology and Infectious Disease

    Meta-Research: Gender inequalities among authors who contributed equally

    Nichole A Broderick, Arturo Casadevall
    An analysis of papers in which two or more authors shared first-author position found that male authors were more likely than female authors to appear first in the author list.
    1. Cancer Biology

    A survey of optimal strategy for signature-based drug repositioning and an application to liver cancer

    Chen Yang, Hailin Zhang ... Hui Wang
    Computational and experimental analyses show that homoharringtonine may be repurposed as an agent for the treatment and prevention of liver cancer.
    1. Epidemiology and Global Health
    2. Medicine

    The impact of lag time to cancer diagnosis and treatment on clinical outcomes prior to the COVID-19 pandemic: A scoping review of systematic reviews and meta-analyses

    Parker Tope, Eliya Farah ... Eduardo L Franco
    Investigating standard lag times prior to the pandemic and identifying key methodological considerations in lag time research can guide future investigations into the impact of time to care for patients with cancer.
    1. Epidemiology and Global Health

    Prediction of type 2 diabetes mellitus onset using logistic regression-based scorecards

    Yochai Edlitz, Eran Segal
    Computational methods were used to develop accurate manual scorecards for early detection of participants at risk of type 2 diabetes based on the UK Biobank database.
    1. Genetics and Genomics
    2. Neuroscience

    Transcriptional cartography integrates multiscale biology of the human cortex

    Konrad Wagstyl, Sophie Adler ... Armin Raznahan
    An atlas of cortical expression for 20,781 genes in the adult human brain, validated against multiscale datasets, from neuroimaging measures of structure and function to molecular cell and layer markers.
  2. Meta-Research: Gender variations in citation distributions in medicine are very small and due to self-citation and journal prestige

    Jens Peter Andersen, Jesper Wiborg Schneider ... Mathias Wullum Nielsen
    In studies of gender disparities in academia, increased focus is required on within-group variability and between-group overlap of distributions when interpreting and reporting results.
    1. Neuroscience

    Meta-Research: Lessons from a catalogue of 6674 brain recordings

    Alexis DJ Makin, John Tyson-Carr ... Marco Bertamini
    A complete public catalogue of brain recording data from a single laboratory has revealed new scientific findings, and has also shed light on aspects of the scientific process, such as statistical power and publication bias.