906 results found
  1. Episode 73: April 2021

    In this episode, we hear about microdosing, bacteria in rivers, parasites and inflammation, aging, and non-inclusive language in science.
  2. Peer Review

    Edited by Peter A Rodgers
    A series of articles exploring how journals, funding agencies and universities review papers, grant applications and people.
  3. Meta-research

    Meta-Research: A Collection of Articles

    Edited by Peter A Rodgers
    The study of science itself is a growing field of research.
  4. One hundred eLife digests shared on Medium

    eLife has now shared plain-language summaries for one hundred eLife articles on the blog-publishing platform Medium.
  5. Episode 46: March 2018

    In this episode, we hear about autism, insulin resistance, Sci-Hub, coping with low levels of oxygen, and how the brain responds to blindness.
  6. Episode 37: March 2017

    In this episode we hear about helping people with paralysis to communicate, how exposing mice to nicotine can affect their sons, scaffold-building parasites, the origins of handedness and plain-language summaries of research.
    1. Immunology and Inflammation

    Systemic hypoxia inhibits T cell response by limiting mitobiogenesis via matrix substrate-level phosphorylation arrest

    Amijai Saragovi et al.
    Systemic hypoxia model reveals the detrimental effect of hypoxia on mitochondrial biogenesis in activated T-cells and points at a new approach for improving viral resistance in patients with respiratory diseases.
    1. Chromosomes and Gene Expression
    2. Computational and Systems Biology

    Gene regulation gravitates toward either addition or multiplication when combining the effects of two signals

    Eric M Sanford et al.
    When two signals increase transcription of the same gene, their combined effect tends to reflect either the sum of the individual increases or the product of the individual fold-changes.
    1. Cell Biology

    Polo-like kinase acts as a molecular timer that safeguards the asymmetric fate of spindle microtubule-organizing centers

    Laura Matellán et al.
    Molecular and cell biology analyses reveal novel roles of Polo-like kinases in establishing non-random segregation patterns of spindle-associated microtubule-organizing centers during mitosis, a phenomenon linked with replicative cell aging.
    1. Neuroscience

    The palmitoyl acyltransferase ZDHHC14 controls Kv1-family potassium channel clustering at the axon initial segment

    Shaun S Sanders et al.
    ZDHHC14 controls palmitoylation and axon initial segment targeting of PSD93 and Kv1-family potassium channels, events that are essential for normal neuronal excitability.

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