290 results found
    1. Cell Biology

    Reactivation of RNA metabolism underlies somatic restoration after adult reproductive diapause in C. elegans

    Nikolay Burnaevskiy et al.
    Morphological and functional rejuvenation upon exit from adult reproductive diapause in C. elegans is independent of germline signaling, but instead involves somatic nucleolar activation and expansion of the RNA pool.
  1. eLife Ambassadors: Progress of key initiatives at the midpoint of the programme

    Meta-research, a popular reproducibility workshop, research into best funding practices and a dedicated blog are just some of the projects underway to support early-career scientists and promote open science.
    1. Cell Biology
    2. Computational and Systems Biology

    A positive-feedback-based mechanism for constriction rate acceleration during cytokinesis in Caenorhabditis elegans

    Renat N Khaliullin et al.
    Positive feedback between contractile ring myosin and compression-driven cortical flow can explain the exponential accumulation of contractile ring components and constriction rate acceleration that ensures timely cell separation during cytokinesis.
  2. Early-Career Advisory Group: Six new members announced

    Three graduate students, two postdocs and one PI will join the advisory group next month.
    1. Human Biology and Medicine
    2. Neuroscience

    Down regulation of vestibular balance stabilizing mechanisms to enable transition between motor states

    Romain Tisserand et al.
    Down regulation of the gain from the vestibular sensory sources prior to the initiation of movement is a motor control solution to overcome the reflex-stabilizing mechanisms to enable motion from a postural orientation.
    1. Physics of Living Systems

    Point of View: Are theoretical results ‘Results’?

    Raymond E Goldstein
    There should be a prominent place for theory within biology papers, both as Results in papers that combine experiment and theory, and as Results in theory papers.
  3. Early-Career Advisory Group: Reflecting on a year of activity

    Over the past year, early-career researchers have built momentum on several initiatives and launched the eLife Ambassadors Programme and Reproducibility Workshops.
    1. Cell Biology
    2. Developmental Biology

    Dual roles for ATP in the regulation of phase separated protein aggregates in Xenopus oocyte nucleoli

    Michael H Hayes et al.
    The equilibrium between solubility and aggregation of proteins in the nucleus is controlled by co-aggregates like RNA and the action of ATP as both an energy source and a destabilizing chemical agent.
  4. A document editor screen overlaying a spreadsheet editor screen

    Stencila – an office suite for reproducible research

    Stencila launches the first version of its word processor and spreadsheet editor designed for researchers.
  5. Peer review: eLife trials a new approach

    eLife authors are being invited to take part in a trial in which they decide how to respond to the issues raised during peer review.

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