298 results found
    1. Genetics and Genomics

    Firefly genomes illuminate parallel origins of bioluminescence in beetles

    Timothy R Fallon et al.
    The first genomic view of beetle luciferase evolution indicates evolutionary independence of luciferase between fireflies and click-beetles, and provide valuable datasets which will accelerate the discovery of new biotechnological tools.
    1. Structural Biology and Molecular Biophysics

    Cryo-EM structure of respiratory complex I at work

    Kristian Parey et al.
    The site of ubiquinone binding observed in the cryo-EM structure of respiratory complex I during turnover supports a two-state stabilization change mechanism.
    1. Neuroscience

    Sparse recurrent excitatory connectivity in the microcircuit of the adult mouse and human cortex

    Stephanie C Seeman et al.
    A high-throughput pipeline for the characterization of cortical connectivity in mouse and human cortex.
  1. Global Science: Barriers in Bangladesh

    Senjuti Saha et al.
    An international effort is needed to overcome the paywalls, customs regulations and lack of local suppliers that hinder research in low- and middle-income countries.
    1. Plant Biology

    Anisotropic growth is achieved through the additive mechanical effect of material anisotropy and elastic asymmetry

    Firas Bou Daher et al.
    Growing upwards in the young seedling is controlled by two cooperative mechanical mechanisms: cellulose orientation in inner tissues and differential elasticity in epidermal cells.
  2. eLife postcard propped up again point of sale display saying Ideas, with lightbulb-shaped jar in foreground

    Evaluating ideas for eLife’s Innovation Initiative

    We consider several questions before providing funding and mentorship for development of a new tool for open research communication.
  3. Annual report: Looking back on 2017

    A reflection on eLife's achievements in 2017, notably in convening and supporting communities, modernising technology for research communication and partnering with early-career researchers.
  4. From the eLife Board: More than just a journal

    Members of the eLife Board of Directors share their views on what we’ve achieved so far and where we’re going next.
    1. Cell Biology

    Reactivation of RNA metabolism underlies somatic restoration after adult reproductive diapause in C. elegans

    Nikolay Burnaevskiy et al.
    Morphological and functional rejuvenation upon exit from adult reproductive diapause in C. elegans is independent of germline signaling, but instead involves somatic nucleolar activation and expansion of the RNA pool.
  5. eLife Ambassadors: Progress of key initiatives at the midpoint of the programme

    Meta-research, a popular reproducibility workshop, research into best funding practices and a dedicated blog are just some of the projects underway to support early-career scientists and promote open science.

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