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    1. Cancer Biology

    Science Forum: Challenges in validating candidate therapeutic targets in cancer

    Jeffrey Settleman et al.
    More than 30 published articles have suggested that a protein kinase called MELK is an attractive therapeutic target in human cancer, but three recent reports describe compelling evidence that it is not.
  1. Scientific Publishing: Room at the top

    Randy Schekman
    Five years after eLife published its first papers, we reflect on our consultative approach to peer review, the challenges of reproducibility, and the need to reform how published research is assessed.
    Editorial
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  2. Point of View: How should novelty be valued in science?

    Barak A Cohen
    An over-emphasis on novelty is having detrimental effects on science.
  3. Peer Review: The pleasure of publishing

    Vivek Malhotra, Eve Marder
    When assessing manuscripts eLife editors look for a combination of rigour and insight, along with results and ideas that make other researchers think differently about their subject.
    Editorial
    Available as:
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  4. Scientific Publishing: A new twist on peer review

    Mark Patterson, Randy Schekman
    eLife is conducting a trial in which authors will decide how to respond to the issues raised during peer review.
    Editorial
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  5. Peer Review: Consultative review is worth the wait

    Stuart RF King
    Editors, reviewers and authors share their experiences of consultative peer review at eLife.
  6. Scientific Publishing: Advancing research

    Mark Patterson et al.
    eLife has introduced a new type of article–the Research Advance–that allows the authors of an eLife paper to publish results that build on their original research paper.
    Editorial
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  7. Scientific Publishing: Coming soon to a screen near you

    Melissa Harrison
    As eLife starts to publish the accepted versions of certain Research Articles, we explain what happens once a manuscript has been accepted for publication.
    Editorial
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  8. Scientific Publishing: A year in the life of eLife

    Randy Schekman et al.
    Improving the peer review process, overcoming the limitations of print journals and providing open access to the very best work in the life and biomedical sciences are three highlights of our first year.
    Editorial
    Available as:
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