487 results found
    1. Developmental Biology and Stem Cells
    2. Immunology

    Symbiosis: Protection from within

    Florent Masson, Bruno Lemaitre
    The development of the tsetse fly immune system relies on a cue from an endosymbiotic bacterium called Wigglesworthia.
    Insight
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    1. Immunology
    2. Microbiology and Infectious Disease

    Blood-stage immunity to Plasmodium chabaudi malaria following chemoprophylaxis and sporozoite immunization

    Wiebke Nahrendorf et al.
    A novel mouse model of immunization against Plasmodium chabaudi involving infectious mosquito bites and drug-treatment elicits protection against blood-stage malaria parasites, and shows that protection is not necessarily life cycle stage-specific.
    Research Article Updated
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  1. Scientific Publishing: Beyond scoops to best practices

    Eve Marder
    Authors submitting a manuscript to eLife are encouraged to upload it to a recognized preprint server at the same time in order to make their results available as quickly and as widely as possible.
    Editorial
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    1. Genomics and Evolutionary Biology
    2. Microbiology and Infectious Disease

    Gene Variation: The double-edged sword of evolution

    Etty Kruzel-Davila, Karl Skorecki
    Two gene variants provide different levels of protection against sleeping sickness, but this comes with an increased risk of developing chronic kidney disease.
    Insight
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    1. Neuroscience

    Freezing suppression by oxytocin in central amygdala allows alternate defensive behaviours and mother-pup interactions

    Elizabeth Rickenbacher et al.
    Oxytocin in the amygdala suppresses freezing of mothers when exposed to a threat in the presence of their offspring, allowing for pup protection and transmission of information about danger from mothers to pups.
    Research Article
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    1. Microbiology and Infectious Disease

    Herpes simplex type 2 virus deleted in glycoprotein D protects against vaginal, skin and neural disease

    Christopher Petro et al.
    An attenuated Herpes simplex type 2 virus deleted in glycoprotein D can be used as an effective vaccine to provide robust transferable humoral immunity and complete protection in murine intravaginal and skin infection models.
    Research Article
    Available as full, typeset article htmlAvailable as authors' accepted manuscript pdf
    1. Immunology
    2. Microbiology and Infectious Disease

    A novel role for lipid droplets in the organismal antibacterial response

    Preetha Anand et al.
    Histones bound to lipid droplets inside cells offer protection against bacteria in flies, and possibly mice, thus suggesting a possible new innate immunity pathway.
    Research Article
    Available as full, typeset article htmlAvailable as authors' accepted manuscript pdf
    1. Immunology

    Epigenetic modulation of type-1 diabetes via a dual effect on pancreatic macrophages and β cells

    Wenxian Fu et al.
    A short treatment of the NOD mouse model of type-1 diabetes with I-BET151, a small molecule bromodomain blocker, provides long-term protection from disease by inducing macrophages to adapt an anti-inflammatory tenor whilst promoting islet β cell regeneration.
    Research Article Updated
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    1. Ecology
    2. Plant Biology

    Correction: Plant defense phenotypes determine the consequences of volatile emission for individuals and neighbors

    Meredith C Schuman et al.
    Correction
    Available as full, typeset article htmlAvailable as authors' accepted manuscript pdf

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