The therapeutic effects of the sleeping pill zolpidem in patients with disorders of consciousness may be due to recruitment of brain cells idling in abnormally low-frequency brain waves.

A new protein–protein interaction motif identified in the polarity protein and tumor suppressor Scribble, and other cortical proteins, controls their interaction with spectrins and is crucial for the localization and function of Scribble.

Autonomous patterns of cell contraction in the context of localized apical extracellular matrix constraints specify tissue stresses that reshape the wing epithelium.

The crystal structure of bacterial RNA polymerase bound to the transcription bubble reveals key features that support the formation of a double-strand/single-strand DNA junction at the upstream edge of the −10 element where bubble formation initiates.

The identification of a neural circuit that drives a specific grooming movement in Drosophila reveals that it may also control movement parameters, such as duration.

Two classes of premotor inhibitory neurons have specific roles in controlling flexor-extensor behaviors in mice, which is the underlying neural mechanism for limb driven movements in terrestrial vertebrates.

Sodium-activated potassium ion currents encoded by the kcnt1 gene delay action potential firing in DRG neurons by activity preceding an action potential.

Local elimination of acetylcholine synthesis in habenular neurons demonstrates a key role for vesicular synergy and neurotransmitter co-release in nicotine dependence.

PDZ-RhoGEF controls adipose tissue abundance and whole body metabolism.

Overexpression of PLK1 triggers oncogenic transformation and transcriptional reprogramming of prostate epithelial cells, which stimulates cell migration and invasion.