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Vascular permeability in retinopathy is regulated by VEGFR2 Y949 signaling to VE-cadherin
Ross O Smith et al.
Pathological vessel leakage in mouse retinopathy models depends on VE-cadherin Y685 phosphorylation status, which in turn is regulated by a signaling cascade originating with VEGFR2 Y949 phosphorylation.
No general relationship between mass and temperature in endothermic species
Kristina Riemer et al.
Data analysis of a large number of species indicates that a negative temperature-mass relationship is not common among species, which has been an ecological assumption for over a century.
Computational and Systems Biology
Integrative analysis of large-scale loss-of-function screens identifies robust cancer-associated genetic interactions
Christopher J Lord et al.
Computational approach to identify reproducible genetic interactions in cancer reveals that they are enriched among protein–protein interaction pairs.
Visualization of currents in neural models with similar behavior and different conductance densities
Leandro M Alonso, Eve Marder
Visualization methods display the dynamics of the currents in conductance-based model neurons, and show how their contribution changes in response to perturbation.
Visual attention modulates the integration of goal-relevant evidence and not value
Pradyumna Sepulveda et al.
Visual attention modulates the integration of the evidence that is most useful for achieving a goal in both perceptual and value-based decisions.
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