Subtypes of dendrite-targeting somatostatin cells segregate into separate networks by specifically connecting with neurons in different layers, forming circuits that could independently control different input pathways to the neocortex.
Caitlin R Bowman, Takako Iwashita, Dagmar Zeithamova
Concepts can be represented at multiple levels of specificity (individual examples, abstract category averages) within a single task across different regions of the brain.
Jessica Jacobs-Li, Weiyi Tang ... Marianne E Bronner
Single-cell transcriptome analysis of sacral compared with vagal neural crest-derived cells in the developing chick enteric nervous system reveals both similarities and differences between these two cell populations.
Retinal ephrin-As gradients provide positional information, through retino-collicular map in the superior colliculus, for topographic alignment of cortico-collicular projections.
Rat orbitofrontal cortex is required to accurately represent outcome distributions, whereas basolateral amygdala is necessary for the facilitation of learning in response to surprising events.
Measuring HIV-1 DNA levels at the time of stopping antiretroviral therapy (when initiated during primary infection) predicts clinical progression and the time taken for plasma viraemia to become detectable.
New evidence shows that when there is uncertainty about an action's goal the motor system creates a single action plan that optimizes task performance rather than averaging multiple potential plans.
Using targeted functional manipulations of neural activity to map neuromodulatory connections can deliver considerable insight into the functional architecture of a behaviorally important network even in the absence of information about its synaptic connectivity.
Paul T Conduit, Jennifer H Richens ... Jordan W Raff
The proteins DSpd-2 and Centrosomin assemble into dynamic scaffolds that build from the inside out around the mother centriole and support centrosome maturation.