Teresa Attenborough, Kate A Rawlinson ... Matthew Berriman
A comprehensive description of gene expression and organisation in the cells that constitute the blood fluke larvae responsible for finding and invading its intermediate host.
Structure-function analysis of the ROR2 cysteine-rich domain reveals a new mechanism of WNT5A reception at the cell surface and provides new insights into the pathogenic mechanisms of Robinow syndrome-driving ROR2 mutations.
A novel role of the mitochondrial BKCa channel involves the metabolic reprogramming of breast cancer cells, facilitating their unrestricted proliferation and O2-independence, which is also of potential clinical relevance.
Chromosomal instability induced in solid tumors can combine with macrophages that are made highly phagocytic to thereby initiate elimination of and immunity against poorly immunogenic tumors in immunocompetent mice.
The endosomal apparatus of African trypanosomes consists a continuous membrane system with functional subdomains rather than distinct compartments for early, late, and recycling endosomes.
The number of sporozoites expelled by mosquitoes that are infected with lab-cultured or naturally circulating Plasmodium falciparum gametocytes is heterogeneous and associated with the sporozoite load in their salivary glands.
Strong reduction in malaria transmission by genetically modified mosquitoes is achieved in the laboratory using a dual gene drive that simultaneously propagates an antiparasitic factor and a parasite-detrimental mosquito mutation.
