Tn5 transposase has direct tagmentation activity towards RNA/DNA hybrids, which is harnessed as a more convenient and faster RNA-seq library construction method and will benefit RNA and chromatin research.
Computational modelling together with experimental manipulation indicate that the stability and turnover of activated Notch is inextricably linked to the regulation of the pace of segmentation clock gene expression in the presomitic mesoderm.
Convolutional neural networks and graph partitioning algorithms can be combined into an easy-to-use tool for segmentation of cells in dense plant tissue volumes imaged with light microscopy.
Shared complexities of backbone segmentation between cartilaginous fishes and tetrapods originate much earlier in vertebrate evolution than previously thought.
A novel, hybrid segmentation technique reveals human heterogeneity in barriers towards a behavior, and is applied to characterize distinct segments in voluntary medical male circumcision.
The organisation of the Drosophila embryo into segmental units is orchestrated by combinatorial regulatory interactions between spatially patterned and temporally patterned transcription factors.
Comparative genomics coupled with genetic and biochemical studies show that central carbon metabolism in fungi can be remodeled by genes originating from bacteria.
The transcriptional coactivator ppargc1a regulates the renal progenitor patterning to delineate boundary formation of differentiated segment populations during nephrogenesis.