RNA polymerase II generates numerous transcript isoforms, including transcripts initiating downstream of the START codon, that are efficiently degraded by the nonsense-mediated mRNA decay pathway.

A unique form of regulation has been observed in the unfolded protein response of S. pombe, along with a novel mechanism of post-transcriptional mRNA processing.

In mice, deleting a long noncoding RNA drives premature aging.

A citizen science game reveals play interest patterns that could inform crowdsourcing experiment design.

Autosomal dominant IRF4 deficiency is the first genetic etiology of Whipple's disease, a very rare chronic condition following a rather common infection by Tropheryma whipplei.

A screen of visual-experience induced changes in newly-synthesized proteins in Xenopus optic tectum identifies unexpected candidate plasticity proteins.

The transfer of O-GlcNAc by EOGT to specific EGF repeats of NOTCH1 promotes DLL4 binding, Notch signaling, and retinal vascular development.

A YTH-domain protein Mmi1 prevents deleterious expression of meiotic proteins by tethering their mRNAs to nuclear foci.