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    1. Neuroscience

    Dreaming with hippocampal damage

    Goffredina Spanò et al.
    A provoked awakening protocol during sleep reveals that selective bilateral hippocampal damage in humans is associated with reduced frequency, quality, and content of dreaming.
    1. Neuroscience

    Thalamic reticular nucleus induces fast and local modulation of arousal state

    Laura D Lewis et al.
    A neural circuit that can selectively induce sleep-like patterns in small regions of the brain demonstrates how sleep and arousal states may be controlled in local brain regions.
    1. Developmental Biology
    2. Plant Biology

    Selective egg cell polyspermy bypasses the triploid block

    Yanbo Mao et al.
    A ménàge à trois introduces extra DNA only to plant embryos, thus skipping endosperm-induced seed hybridization barriers.
    1. Neuroscience

    Distinct roles of striatal direct and indirect pathways in value-based decision making

    Shinae Kwak, Min Whan Jung
    The direct and indirect pathways of the dorsal striatum play indispensable roles in value-dependent action selection and value learning, respectively.
    1. Computational and Systems Biology
    2. Genetics and Genomics

    Detecting adaptive introgression in human evolution using convolutional neural networks

    Graham Gower et al.
    Convolutional neural networks are an effective tool for detecting archaic adaptive introgression from genomic data.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Quantitative proteomics reveals the selectivity of ubiquitin-binding autophagy receptors in the turnover of damaged lysosomes by lysophagy

    Vinay V Eapen et al.
    A combination of spatial proteomic and autophagic flux approaches was used to reveal the landscape of turnover of damaged lysosomes, demonstrating a key role for the autophagy receptor TAX1BP1 and its associated kinase TBK1 in both HeLa cells and iNeurons.
    1. Evolutionary Biology

    Multifactorial processes underlie parallel opsin loss in neotropical bats

    Alexa Sadier et al.
    Parallel losses of short-wave light sensitivity in diverse bats occurred through independent changes at multiple steps in the conversion of genotype into functional phenotype, including pre-, during, and post-transcription.
    1. Neuroscience

    Behavioural and neural signatures of perceptual decision-making are modulated by pupil-linked arousal

    Jochem van Kempen et al.
    A direct relationship between pupil diameter and electrophysiological correlates of attention, sensory stimulus processing and target detection was observed demonstrating that arousal has a substantial influence on perceptual decision-making.
    1. Genetics and Genomics

    Background selection and biased gene conversion affect more than 95% of the human genome and bias demographic inferences

    Fanny Pouyet et al.
    Background selection and GC-biased gene conversion impact the human genome to a much larger extent than previously recognized in low and high recombination rate regions, respectively.
    1. Neuroscience

    Sucrose intensity coding and decision-making in rat gustatory cortices

    Esmeralda Fonseca et al.
    The neural representation of perceived sucrose intensity was contained in the firing rate and spike-timing of a 'small' population of neurons distributed across the Insula and Orbitofrontal taste cortices.