Joleen JH Traets, Servaas N van der Burght ... Jeroen S van Zon
Differential binding kinetics of a master regulator to its target promoters can prevent spontaneous cell fate loss in a Caenorhabditis elegans neuron whose fate is controlled by a reversible switch.
Johannes Stratmann, Hugo Gabilondo ... Stefan Thor
A combination of temporal and sub-temporal genes combine to move the stem cell through different competence windows to generate different cell types at different time-points in Drosophila.
Emilia Dimitrova, Takashi Kondo ... Robert J Klose
The ZF-CxxC protein FBXL19 recruits kinase-associated Mediator to CpG islands of silent developmental genes in embryonic stem cells, which primes these genes for activation during differentiation and is required for embryonic development.
Laura Pereira, Florian Aeschimann ... Oliver Hobert
The timing of sexual differentiation in the brain of the nematode Caenorhabditis elegans is controlled by a phylogenetically conserved pathway of gene regulatory factors.
Lauren J Donovan, William C Spencer ... Evan S Deneris
A continuously expressed LIM HD factor, Lmx1b, acts at successive stages to orchestrate the progressive morphological maturation of a long-range profusely arborized neuromodulatory axonal projection pathway.
Ethan Ozment, Arianna N Tamvacakis ... Nagayasu Nakanishi
Developmental genetics of sea anemone mechanosensory neurons provides insights into the deep evolutionary history of mechanoreceptor development in animals.