29 results found
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Structure of the germline genome of Tetrahymena thermophila and relationship to the massively rearranged somatic genome

    Eileen P Hamilton, Aurélie Kapusta ... Robert S Coyne
    The model organism Tetrahymena thermopile carries two nuclei with distinct genomes: an unrearranged germline genome with five chromosomes, and a somatic genome reduced in size by a third and with 181 chromosomes.
    1. Developmental Biology
    2. Plant Biology

    Cross-species functional diversity within the PIN auxin efflux protein family

    Devin Lee O'Connor, Samuel Elton ... Ottoline Leyser
    Comparative genetics between distant plant species shows that for the PIN auxin transport proteins differential membrane and tissue-level accumulation, transport activity, and interaction result in different functional properties in the shoot post transcription.
    1. Evolutionary Biology

    Free-living human cells reconfigure their chromosomes in the evolution back to uni-cellularity

    Jin Xu, Xinxin Peng ... Chung-I Wu
    Human cell lines regress to become ‘de-sexualized’ by reconfiguring to a 2:3 X/A ratio of high fitness, thus shedding light on the evolution of mammalian sex chromosomes.
    1. Neuroscience

    Response to comment on "Magnetosensitive neurons mediate geomagnetic orientation in Caenorhabditis elegans"

    Andres Vidal-Gadea, Chance Bainbridge ... Jonathan Pierce-Shimomura
    A reanalysis of data from a challenge by Landler et al. (2018) and our Vidal-Gadea et al. (2015) study reinforce our original finding that C. elegans is a suitable model system to study magnetoreception.
    1. Chromosomes and Gene Expression

    Six domesticated PiggyBac transposases together carry out programmed DNA elimination in Paramecium

    Julien Bischerour, Simran Bhullar ... Mireille Bétermier
    The machinery that carries out programmed DNA rearrangements is composed of domesticated transposases. One is catalytically active, five play architectural function essential for the accuracy of the process.
    1. Genetics and Genomics

    Firefly genomes illuminate parallel origins of bioluminescence in beetles

    Timothy R Fallon, Sarah E Lower ... Jing-Ke Weng
    The first genomic view of beetle luciferase evolution indicates evolutionary independence of luciferase between fireflies and click-beetles, and provide valuable datasets which will accelerate the discovery of new biotechnological tools.
    1. Evolutionary Biology

    Changes to social feeding behaviors are not sufficient for fitness gains of the Caenorhabditis elegans N2 reference strain

    Yuehui Zhao, Lijiang Long ... Patrick T McGrath
    Use of experimental manipulation demonstrates that social/solitary feeding behaviors are unrelated to the fitness gains conferred by causative alleles in two previously identified genes.
    1. Evolutionary Biology

    Evolution of Yin and Yang isoforms of a chromatin remodeling subunit precedes the creation of two genes

    Wen Xu, Lijiang Long ... Patrick T McGrath
    Gene sharing through different isoforms can precede the formation of independent genes.
    1. Structural Biology and Molecular Biophysics

    Kin discrimination in social yeast is mediated by cell surface receptors of the Flo11 adhesin family

    Stefan Brückner, Rajib Schubert ... Hans-Ulrich Mösch
    Structural, biophysical and physiological analysis reveals how yeast cell surface adhesins evolved to confer self-nonself discrimination in single cells and whole populations.
    1. Evolutionary Biology
    2. Genetics and Genomics

    The yeast mating-type switching endonuclease HO is a domesticated member of an unorthodox homing genetic element family

    Aisling Y Coughlan, Lisa Lombardi ... Kenneth H Wolfe
    A family of homing genetic elements that look like inteins but work differently is the progenitor of the endonuclease that enables Saccharomyces cerevisiae to change its mating type.

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