An unbiased model for the self-organisation of the Golgi apparatus displays either anterograde vesicular transport or cisternal maturation depending on ratios of budding, fusion and biochemical conversion rates.
In a developing yeast colony, cells go from homogeneous states to spatially organized, specialized metabolic states, and the new metabolic states depend on resources produced by the original state.
Two cooperative populations of yeast cells that cannot distinguish between cooperative partners and cheating intruders can still self-organize into clusters that exclude cheaters.
Quantitative, experimentally testable predictions allow discrimination between contraction mechanisms in disordered actomyosin and microtubule/motor bundles.
An experimentally constrained multiscale mathematical model predicts that branched actin networks self-organize at endocytic sites and bend to produce force, which was verified with cryo-electron tomography of intact cells.
A computational model for the formation of neural networks of grid cells in virtual bats suggests that the highly ordered networks presumed to support spatial navigation in two dimensions cannot be routinely established in three-dimensional space.