1,122 results found
    1. Physics of Living Systems
    2. Stem Cells and Regenerative Medicine

    Global and local tension measurements in biomimetic skeletal muscle tissues reveals early mechanical homeostasis

    Arne D Hofemeier et al.
    Combining global and local force measurements of reconstituted muscle tissue using a new chamber system that is compatible with high-resolution microscopy shows mechanical homeostasis already within a week.
    1. Plant Biology

    A multifaceted analysis reveals two distinct phases of chloroplast biogenesis during de-etiolation in Arabidopsis

    Rosa Pipitone et al.
    Serial-Block-Face Scanning Electron Microscopy (SBF-SEM) associated with biomolecular analysis show that chloroplast differentiation proceeds by distinct ‘structure establishment’ and ‘chloroplast proliferation’ phases, each with differential protein and lipid regulation.
    1. Medicine
    2. Neuroscience

    Point of View: Open science takes on Parkinson’s disease

    Ekemini AU Riley, Randy Schekman
    The ASAP initiative promotes open and collaborative practices, and works with other foundations and projects in an effort to understand the mechanisms responsible for the onset and progression of Parkinson's.
    1. Ecology
    2. Genetics and Genomics

    Education and Outreach: March Mammal Madness and the power of narrative in science outreach

    Katie Hinde et al.
    Hypothetical battles between animals can be used to interest the general public in biology.
    1. Cancer Biology

    Convergent organization of aberrant MYB complex controls oncogenic gene expression in acute myeloid leukemia

    Sumiko Takao et al.
    Definition of leukemia gene expression mechanisms reveals general principles of cancer gene control and offers a pharmacologic strategy for its therapeutic reprogramming.
    1. Epidemiology and Global Health

    Antimicrobial resistance and COVID-19: Intersections and implications

    Gwenan M Knight et al.
    COVID-19 will have an ongoing impact on antimicrobial resistance acquisition, transmission, and burden, requiring the close attention of researchers globally to generate a complete evidence base for the shifted dynamics.
    1. Neuroscience

    A new model of decision processing in instrumental learning tasks

    Steven Miletić et al.
    A new model is presented to simultaneously study the latent cognitive processes underlying decision making and instrumental learning.
    1. Cancer Biology

    SATB2 induction of a neural crest mesenchyme-like program drives melanoma invasion and drug resistance

    Maurizio Fazio et al.
    A genetic discovery screen for epigenetic factors accelerating melanoma development in vivo identifies SATB2 as a driver of tumor invasion and resistance to FDA-approved BRAF-targeted inhibitor Vemurafenib.
    1. Cell Biology
    2. Developmental Biology

    Visualizing the metazoan proliferation-quiescence decision in vivo

    Rebecca C Adikes et al.
    During organismal development, CDK activity at mitotic exit is predictive of future cell behavior, indicating whether a cell will divide again or enter a quiescent state.
    1. Cell Biology
    2. Genetics and Genomics

    An integrative study of five biological clocks in somatic and mental health

    Rick Jansen et al.
    An integrative study of five biological clocks in somatic and mental health indicate that one's biological age is best reflected by combining aging measures from multiple cellular levels.

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