103 results found
    1. Cancer Biology

    KLK3/PSA and cathepsin D activate VEGF-C and VEGF-D

    Sawan Kumar Jha, Khushbu Rauniyar ... Michael Jeltsch
    Both VEGF-C and VEGF-D can be activated by KLK3/PSA and Cathepsin D, producing two novel VEGF-C forms and the known VEGFR-2-specific form of VEGF-D.
    1. Ecology
    2. Evolutionary Biology

    Seminal fluid compromises visual perception in honeybee queens reducing their survival during additional mating flights

    Joanito Liberti, Julia Görner ... Boris Baer
    After insemination, honeybee queens experience a rapid reduction in vision and flight performance, consistent with an ongoing sexual conflict over the number of mating flights that queens embark on.
    1. Evolutionary Biology

    Sperm competition risk drives rapid ejaculate adjustments mediated by seminal fluid

    Michael J Bartlett, Tammy E Steeves ... Patrice C Rosengrave
    Seminal fluid harbours the as yet unknown mechanism that facilitates rapid adjustment of sperm velocity in response to changing sperm competition risk.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Drosophila seminal sex peptide associates with rival as well as own sperm, providing SP function in polyandrous females

    Snigdha Misra, Mariana F Wolfner
    A seminal protein from a mating-male can bind sperm previously stored in his mate, providing direct benefits to the sperm from the prior male that mated with her.
    1. Evolutionary Biology
    2. Genetics and Genomics

    The seminal odorant binding protein Obp56g is required for mating plug formation and male fertility in Drosophila melanogaster

    Nora C Brown, Benjamin Gordon ... Mariana Federica Wolfner
    A functional genetics approach reveals a novel role for odorant binding proteins in post-mating processes, with complex mechanisms of evolutionary change across closely related insect species.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    A molecular tweezer antagonizes seminal amyloids and HIV infection

    Edina Lump, Laura M Castellano ... Jan Münch
    CLR01 is a small molecule that could be an effective topical microbicide to eliminate HIV (and other enveloped viruses), and to antagonize host-encoded amyloid fibrils that promote HIV infection.
    1. Ecology

    Sexual selection gradients change over time in a simultaneous hermaphrodite

    Jeroen NA Hoffer, Janine Mariën ... Joris M Koene
    The quantification of sexual selection reveals that it is important to consider the chosen time frame of measurement as well as the sexual system.
    1. Structural Biology and Molecular Biophysics

    Semen amyloids participate in spermatozoa selection and clearance

    Nadia R Roan, Nathallie Sandi-Monroy ... Warner C Greene
    Ex vivo characterization of the interaction of human sperm with semen factors reveals that semen amyloids, previously discovered due to their ability to enhance HIV infection, serve a physiological function by promoting disposal of the defective sperm.
    1. Chromosomes and Gene Expression

    Paternal nicotine exposure alters hepatic xenobiotic metabolism in offspring

    Markus P Vallaster, Shweta Kukreja ... Oliver J Rando
    A novel paternal effect based on nicotine exposure reveals that offspring exhibit an adaptive, yet nonspecific, resistance to multiple toxins.
    1. Evolutionary Biology

    Sperm competition: The need for speed

    Tom Pizzari
    A change in social status can quickly lead to a change in the quality of the seminal fluid produced by a male Chinook salmon as he responds to increased reproductive competition from higher-status males.
    Version of Record
    Insight

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