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    1. Computational and Systems Biology
    2. Neuroscience

    Towards deep learning with segregated dendrites

    Jordan Guerguiev et al.
    A multi-compartment spiking neural network model demonstrates that biologically feasible deep learning can be achieved if sensory inputs and higher-order feedback are received by different dendritic compartments.
  1. Scientific Publishing: How early-career researchers are shaping eLife

    Mark Patterson, Randy Schekman
    Journals can benefit from listening to graduate students, postdocs and newly-independent group leaders.
    Editorial
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    1. Neuroscience

    Convergence of pontine and proprioceptive streams onto multimodal cerebellar granule cells

    Cheng-Chiu Huang et al.
    Individual granule cells within the cerebellum-the region of the brain that coordinates movement and supports the learning of new motor skills-receive both sensory and motor input streams: an arrangement that may help the brain to use feedback to fine-tune movement.
  2. Careers: eLife and early career researchers

    Randy Schekman et al.
    There are many reasons for submitting your best work to eLife, especially if you are an early career researcher.
    Editorial
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    1. Neuroscience

    Intracortical Microstimulation: Regaining the senses of touch and movement

    Victor de Lafuente
    Artificially activating certain neurons in the cortex can make a tetraplegic patient feel naturalistic sensations of skin pressure and arm movement.
    Insight
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    1. Developmental Biology

    Organ Size: Connecting physical cues and tissue patterning

    Damian Dalle Nogare, Ajay B Chitnis
    Insight
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    1. Microbiology and Infectious Disease

    Research Culture: Co-reviewing and ghostwriting by early-career researchers in the peer review of manuscripts

    Gary S McDowell et al.
    Early career researchers commonly peer review manuscripts on behalf of invited reviewers, often without receiving feedback or being named to the journal.
  3. Peer Review: Decisions, decisions

    Peter Rodgers
    Journals are exploring new approaches to peer review in order to reduce bias, increase transparency and respond to author preferences.
  4. Plain-language Summaries of Research: Something for everyone

    Sarah Shailes
    Journals and other scientific organizations produce a diverse variety of plain-language summaries.