The anchoring properties of Ca_V β2 subunits to the plasma membrane determine the biophysical states of Ca_V2.2 channels by regulating PIP₂ coupling to the nonspecific phospholipid-binding site in the I–II loop.

An iterative self-assembling algorithm identifies the intrinsic structures in single-cell transcriptomic data and helps to discover new cell populations that are undetectable by existing methods.

Basal ganglia gene coexpression patterns shift across the sensorimotor critical period for vocal learning.

The numerous reports in support of action-value representation in the striatum are based on statistical analyses that are subject to two critical confounds and, thus, this long-held belief of striatal action-value representation should be retested using different experiments and analyses.

In the absence of centrioles, components of pericentriolar material can self-organize into a single compact microtubule-organizing center through dynein-mediated transport of pericentrin-containing protein complexes if CAMSAP- and Golgi-mediated pathways of microtubule minus-end stabilization and anchoring are disabled.

Knockdown of PHOX2B in the chemosensitive area of the retrotrapezoid nucleus of adult rats reduces CO₂ responses and the expression of the proton sensors TASK2 and GPR4.

A mathematical model predicts that cell cycle duration acts as a transcriptional filter and directly affects cell diversity in early eukaryotic development.

Gradual downregulation of each of the subunits of the evolutionary-conserved exocyst holocomplex shows that the complex is required for biogenesis, maturation, and exocytosis of secretory granules in Drosophila salivary glands.

A systematical study of pslG mutants at both a single cell and community level reveals the importance of intracellular glycosyl hydrolase PslG on the cell fate and biofilm development of P. aeruginosa, an opportunistic pathogen that can cause persistent infections.

Depletion of the mechanosensitive ion channel PEZO-1 in C. elegans disrupts the sheath and spermathecae cells to disrupt oocyte ovulation, resulting in crushed oocytes.