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Page 2 of 196
    1. Neuroscience

    Can sleep protect memories from catastrophic forgetting?

    Oscar C González, Yury Sokolov ... Maxim Bazhenov
    Computational modeling predicts that sleep replay plays a protective role against catastrophic forgetting by revealing synaptic mechanisms allowing overlapping populations of neurons to store multiple interfering memories.
    1. Computational and Systems Biology
    2. Developmental Biology

    Modelling the emergence of whisker barrels

    Sebastian S James, Leah A Krubitzer, Stuart P Wilson
    Whisker barrels provide clues about neocortical development, as computer modelling shows that barrels can self-organize, based on competition between adjacent thalamocortical axons, suggesting that genetic instruction plays a secondary role.
    1. Neuroscience

    Spike frequency adaptation supports network computations on temporally dispersed information

    Darjan Salaj, Anand Subramoney ... Wolfgang Maass
    Spike frequency adaptation provides spiking neural networks with long short-term memory.
    1. Cell Biology
    2. Neuroscience

    Activity regulates a cell type-specific mitochondrial phenotype in zebrafish lateral line hair cells

    Andrea McQuate, Sharmon Knecht, David W Raible
    The highly metabolically active hair cells of the zebrafish lateral line have a distinct mitochondrial phenotype consisting of small mitochondria apically and large, networked mitochondrion basally, demonstrating a nonuniform mitochondrial architecture that is sculpted by cellular activity.
    1. Neuroscience

    Cadherin preserves cohesion across involuting tissues during C. elegans neurulation

    Kristopher M Barnes, Li Fan ... Zhirong Bao
    A coordinated tissue movement during C. elegans central nervous system internalization reveals a novel role for HMR-1/cadherin in maintaining cohesion, and extends the concept of neurulation beyond vertebrates.
    1. Neuroscience

    Early-generated interneurons regulate neuronal circuit formation during early postnatal development

    Chang-Zheng Wang, Jian Ma ... Yong-Chun Yu
    Early-generated interneurons are more mature in intrinsic properties and neuronal connectivity during early postnatal stage, and are critical for proper spontaneous network synchronization and the wiring of immature cortical circuits.
    1. Neuroscience

    A role for descending auditory cortical projections in songbird vocal learning

    Yael Mandelblat-Cerf, Liora Las ... Michale S Fee
    Midbrain dopaminergic neurons and a cortex-like structure called the arcopallium form part of a circuit that enables young songbirds to compare their own song with a template stored in memory, and use any discrepancies to improve their performance.
    1. Neuroscience

    Using subthreshold events to characterize the functional architecture of the electrically coupled inferior olive network

    Yaara Lefler, Oren Amsalem ... Yosef Yarom
    Non-synaptic electrical events recorded simultaneously from pairs of neurons in the inferior olive nucleus enables accurate estimation of the size and of the clustered organization of the electrically coupled network.
    1. Neuroscience

    Cholecystokinin facilitates motor skill learning by modulating neuroplasticity in the motor cortex

    Hao Li, Jingyu Feng ... Jufang He
    CCK released from the neural projections from the rhinal cortex to the motor cortex modulates neural plasticity and facilitates motor skill learning.
    1. Neuroscience

    Motor thalamus supports striatum-driven reinforcement

    Arnaud L Lalive, Anthony D Lien ... Anatol C Kreitzer
    While the basal ganglia have long been thought to mediate learning through dopamine-dependent striatal plasticity, their regulation of motor thalamus plays an unexpected and critical role in reinforcement.