3,376 results found
    1. Structural Biology and Molecular Biophysics

    Decoding WW domain tandem-mediated target recognitions in tissue growth and cell polarity

    Zhijie Lin et al.
    A systematic and quantitative investigation showing how highly specific WW domain-mediated protein-protein interaction network is organized in cell growth and polarity.
    1. Evolutionary Biology
    2. Plant Biology

    Natural selection and repeated patterns of molecular evolution following allopatric divergence

    Yibo Dong et al.
    The genomic architecture of allopatric species is a mosaic of many conserved genes and a few adaptive ones, reflecting balance between conservation of ancestral functions and evolution of new features.
    1. Developmental Biology
    2. Evolutionary Biology

    The alternative regenerative strategy of bearded dragon unveils the key processes underlying vertebrate tooth renewal

    Lotta Salomies et al.
    Analysis of bearded dragon model reveals a novel tooth replacement strategy that demonstrates the critical importance of epithelial patterning, cell migration, and putative stem cell functional specialization in tissue regeneration.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Heparan sulfates are critical regulators of the inhibitory megakaryocyte-platelet receptor G6b-B

    Timo Vögtle et al.
    Heparan sulfates in the vessel wall bind and regulate signaling from the megakaryocyte/platelet-specific inhibitory receptor G6b-B, a critical regulator of platelet homeostasis.
    1. Biochemistry and Chemical Biology

    Oxygen Sensors: When is a target not a target?

    David C Bersten, Daniel J Peet
    Cells rely on prolyl hydroxylase enzymes to sense low levels of oxygen, but they might act on fewer targets than previously thought.
    Insight
    Available as:
    • HTML
    • PDF
    1. Neuroscience

    Increased expression of heme-binding protein 1 early in Alzheimer's disease is linked to neurotoxicity

    Oleksandr Yagensky et al.
    Increased levels of brain Hebp1 starting from the presymptomatic stage of Alzheimer’s disease contributes to progressive neuronal loss by triggering mitochondrial-dependent apoptosis in neurons exposed to elevated heme.
    1. Genetics and Genomics
    2. Plant Biology

    Epigenetic silencing of a multifunctional plant stress regulator

    Mark Zander et al.
    Interplay between histone demethylation and chromatin remodeling shapes the chromatin environment of the essential stress regulator ETHYLENE-INSENSITIVE2.
    1. Developmental Biology

    Actomyosin regulation by Eph receptor signaling couples boundary cell formation to border sharpness

    Jordi Cayuso et al.
    Boundary cell identity and sharpening of borders are coupled in hindbrain development since both are regulated by mechanical tension.
    1. Ecology
    2. Evolutionary Biology

    Seminal fluid compromises visual perception in honeybee queens reducing their survival during additional mating flights

    Joanito Liberti et al.
    After insemination, honeybee queens experience a rapid reduction in vision and flight performance, consistent with an ongoing sexual conflict over the number of mating flights that queens embark on.
    1. Developmental Biology

    Notch signalling maintains Hedgehog responsiveness via a Gli-dependent mechanism during spinal cord patterning in zebrafish

    Craig T Jacobs, Peng Huang
    Genetic analyses combining photoconvertible cell signalling reporters with gain- and loss-of function manipulations reveal a novel role for Notch signalling in controlling Hedgehog response in neural progenitor cells.

Refine your results by:

Type
Research categories