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Mechano-dependent signaling by Latrophilin/CIRL quenches cAMP in proprioceptive neurons
Nicole Scholz et al.
Metabotropic mechanosensing occurs through an adhesion-type G protein-coupled receptor.
Biochemistry and Chemical Biology
Structural Biology and Molecular Biophysics
Asymmetric activation mechanism of a homodimeric red light-regulated photoreceptor
Geoffrey Gourinchas et al.
Molecular insights to phytochrome activation and signal transduction over long distances enable the allosteric regulation of enzymatic effectors.
Computational and Systems Biology
Elastic force restricts growth of the murine utricle
Ksenia Gnedeva et al.
Computational modeling and molecular-biological analysis reveal the role of mechanical force and downstream Yap signaling in growth control during the development and regeneration of sensory epithelium of the inner ear.
Immunology and Inflammation
A pain-mediated neural signal induces relapse in murine autoimmune encephalomyelitis, a multiple sclerosis model
Yasunobu Arima et al.
Pain sensation induces relapse in a mouse model of multiple sclerosis via a sensory-sympathetic signaling pathway.
The p38 MAP kinase pathway modulates the hypoxia response and glutamate receptor trafficking in aging neurons
Eun Chan Park, Christopher Rongo
The subcellular localization of the prolyl hydroxylase oxygen sensor in
neurons is regulated by p38 MAP kinase signaling.
Keratinocytes mediate innocuous and noxious touch via ATP-P2X4 signaling
Francie Moehring et al.
Keratinocytes are critical for normal innocuous and noxious touch through their mechanically evoked ATP release and subsequent signaling to P2X4 channels on sensory neurons.
Tachykinin acts upstream of autocrine Hedgehog signaling during nociceptive sensitization in
Seol Hee Im et al.
equivalent of Substance P signaling modulates nociceptive sensitization by regulating Hedgehog signaling within nociceptive sensory neurons.
Correction: Orbitofrontal neurons acquire responses to ‘valueless’ Pavlovian cues during unblocking
Michael A McDannald et al.
Hypoxia: Adapt or avoid
Ganesh K Kumar
Biosensors: Plant biologists FRET over stress
Won-Gyu Choi, Simon Gilroy
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