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C. elegans EFHC1 influences neuronal transmission through the cilium and the synapse.

Serial-section EM analysis uncovers the CNS connectome of a Ciona larva, the second of any entire nervous system, and exposes left-right asymmetries in its synaptic circuits.

A knockin mouse line was made to label endogenous AMPA receptors, enabling direct observation of synaptic plasticity in behaving animals with single-synapse resolution across the entire brain.

Postnatal, postsynaptic loss of FMRP specifically weakens callosal synaptic inputs onto L2/3 pyramidal neurons, in requirement ofnormal sensory experience, through downregulating AMPA receptor transmission and without affecting local synaptic inputs during cortical circuit development.

FlyBrainLab is an open-source computing platform that integrates 3D exploration and visualization of diverse Drosophila connectomic/synaptomic datasets with interactive exploration of the functional logic of modeled executable brain circuits.

The spatial regulation of gene expression within neurons occurs primarily at the level of local translation rather than by stimulus-induced RNA targeting from nucleus to synapse.

Behaviorally-driven expression of the immediate early gene transcription factor NPAS4 changes local circuit connectivity and short-term plasticity by selectively recruiting CCK basket cell synapses to pyramidal neuron somas.

Neocortical synapses in layer 4 of the human temporal lobe neocortex were quantitatively characterized, at the subcellular level, using high-end, high-resolution electron microscopy and 3D-volume reconstructions.

Neurons are mapped for developmental features (lineage, hemilineage, temporal identity) and connectomic features (morphology, synapse localization and connectivity) to reveal correlations that can be tested experimentally.

A pair of interneurons in C. elegans condenses information from multiple sensory neurons into a uniform response, using an AND-gate logic to represent a stimulus with positive valence.