1,890 results found
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Structural diversity of oligomeric β-propellers with different numbers of identical blades

    Evgenia Afanasieva et al.
    A protein fragment forms different folded structures when amplified to different copy numbers within a single polypeptide chain.
    1. Chromosomes and Gene Expression

    Genome Organization: Painting chromosomes in the nucleus

    Cori K Cahoon, Diana E Libuda
    A multiplexed approach to DNA FISH experiments has been used to visualize the three-dimensional organization of chromosomes and specific chromosomal regions in C. elegans..
    Insight
    Available as:
    • HTML
    • PDF
    1. Cancer Biology

    Philosophy of Biology: Characterizing causality in cancer

    Elena Rondeau et al.
    Ideas about causality from philosophy can help scientists to better understand how cancerous tumors grow and spread in the body.
    1. Cancer Biology
    2. Genetics and Genomics

    Tumor Evolution: Finding the mutations that drive resistance

    Nadine Bley
    Mutations that allow tumors to evolve and become resistant to treatment can be readily identified with a new sequencing approach.
    Insight
    Available as:
    • HTML
    • PDF
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Fossils: A new home for microbes

    Raphael Eisenhofer, Alan Cooper
    Modern microorganisms growing in fossils provide major challenges for researchers trying to detect ancient molecules in the same fossils.
    Insight
    Available as:
    • HTML
    • PDF
    1. Epidemiology and Global Health
    2. Plant Biology

    Plant Pathology: Plasmid-powered evolutionary transitions

    Ryan A Melnyk, Cara H Haney
    The acquisition of a virulence plasmid is sufficient to turn a beneficial strain of Rhodococcus bacteria into a pathogen.
    Insight
    Available as:
    • HTML
    • PDF
    1. Ecology
    2. Chromosomes and Gene Expression

    Emerging Technology: Concerning RNA-guided gene drives for the alteration of wild populations

    Kevin M Esvelt et al.
    Combining CRISPR/Cas9 genome editing with gene drives may enable scientists to reversibly edit the genomes of diverse wild populations, an advance that could help eliminate diseases, support sustainable agriculture, and control invasive species.
    1. Chromosomes and Gene Expression

    Sustained TNF-α stimulation leads to transcriptional memory that greatly enhances signal sensitivity and robustness

    Zuodong Zhao et al.
    Sustained TNF-α induction consolidates transcriptional memory for faster, stronger, and more sensitive subsequent induction in an active DNA demethylation-dependent manner for memory genes including CALCB, a therapeutic target for migraine.
    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    16p11.2 microdeletion imparts transcriptional alterations in human iPSC-derived models of early neural development

    Julien G Roth et al.
    A model of in vitro human corticogenesis identifies alterations in gene expression caused by loss of 16p11.2 CNV genes in hiPSC-derived progenitor cells.
    1. Neuroscience

    Feeding state functionally reconfigures a sensory circuit to drive thermosensory behavioral plasticity

    Asuka Takeishi et al.
    Starvation modulates thermotaxis behaviors in C. elegans via functional reconfiguration of a sensory network by gut-brain signaling.

Refine your results by:

Type
Research categories