11,566 results found
    1. Evolutionary Biology

    Neurocranial anatomy of an enigmatic Early Devonian fish sheds light on early osteichthyan evolution

    Alice M Clement, Benedict King ... John A Long
    Stunning new scan data of an enigmatic fish from the Early Devonian of Australia, Ligulalepis, is identified as a stem osteichthyan, specifically, as the sister taxon to the 'psarolepids' plus crown osteichthyans.
    1. Microbiology and Infectious Disease

    Quantification of sporozoite expelling by Anopheles mosquitoes infected with laboratory and naturally circulating P. falciparum gametocytes

    Chiara Andolina, Wouter Graumans ... Teun Bousema
    The number of sporozoites expelled by mosquitoes that are infected with lab-cultured or naturally circulating Plasmodium falciparum gametocytes is heterogeneous and associated with the sporozoite load in their salivary glands.
    1. Cell Biology
    2. Computational and Systems Biology

    CDK control pathways integrate cell size and ploidy information to control cell division

    James Oliver Patterson, Souradeep Basu ... Paul Nurse
    DNA concentration, cyclin levels, phosphatase activity, and CDK phosphorylation combine to directly link cell size to cell division.
    1. Microbiology and Infectious Disease

    PGFinder, a novel analysis pipeline for the consistent, reproducible, and high-resolution structural analysis of bacterial peptidoglycans

    Ankur V Patel, Robert D Turner ... Stéphane Mesnage
    PGFinder is an open-source software dedicated to the analysis of peptidoglycan mass spectrometry data that paves the way for peptidoglycomics.
    1. Computational and Systems Biology
    2. Neuroscience

    Uncovering circuit mechanisms of current sinks and sources with biophysical simulations of primary visual cortex

    Atle E Rimehaug, Alexander J Stasik ... Anton Arkhipov
    A biophysically detailed model of mouse primary visual cortex reproduces, in a quantitative manner, experimentally recorded spikes and local field potentials, and suggests mechanisms that form current sinks and sources in vivo.
    1. Computational and Systems Biology
    2. Epidemiology and Global Health

    The intractable challenge of evaluating cattle vaccination as a control for bovine Tuberculosis

    Andrew James Kerr Conlan, Martin Vordermeier ... James LN Wood
    Natural transmission experiments should be prioritised over risky and expensive field trials, in order to establish the impact of cattle vaccination on the transmission of bovine Tuberculosis.
    1. Cell Biology
    2. Medicine

    An experimental test of the effects of redacting grant applicant identifiers on peer review outcomes

    Richard K Nakamura, Lee S Mann ... Bruce Reed
    Redaction, intended to obscure personal and institutional identity, reduced the gap between Black vs. White applicants in simulated review of real NIH scientific grant applications, thus providing qualified support for double-blinded models of peer review.
    1. Evolutionary Biology

    A Bayesian approach to dynamic homology of morphological characters and the ancestral phenotype of jawed vertebrates

    Benedict King, Martin Rücklin
    The ancestor of all known jawed vertebrates possessed a maxilla and premaxilla and was similar in morphology to the 'maxillate placoderms' from China.
    1. Ecology
    2. Neuroscience

    BiteOscope, an open platform to study mosquito biting behavior

    Felix JH Hol, Louis Lambrechts, Manu Prakash
    A new tool to visualize blood-feeding mosquitoes in high resolution and quantitatively characterize their behavior sheds light on contact-dependent sensing and blood-feeding dynamics of several medically relevant mosquito species.
    1. Structural Biology and Molecular Biophysics

    Her2 activation mechanism reflects evolutionary preservation of asymmetric ectodomain dimers in the human EGFR family

    Anton Arkhipov, Yibing Shan ... David E Shaw
    The structural basis for Her2's role as a dedicated heterodimerization partner for other EGFR family receptors is elucidated with long-timescale atomistic simulations.

Refine your results by:

Type
Research categories