7,205 results found
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Pattern regulation in a regenerating jellyfish

    Chiara Sinigaglia et al.
    Clytia jellyfish regenerate body shape and organs through a mechanically driven process that coordinates tissue remodeling, localized proliferation, and precursor migration and promotes Wnt signaling at a muscle-based landmark.
    1. Neuroscience

    A circuit mechanism for decision-making biases and NMDA receptor hypofunction

    Sean Edward Cavanagh et al.
    Ketamine, an NMDA receptor antagonist and experimental model for schizophrenia, produces decision-making deficits in monkeys, which are predicted by a lowering of cortical excitation-inhibition balance in a spiking circuit model.
    1. Neuroscience

    Unexplained repeated pregnancy loss is associated with altered perceptual and brain responses to men’s body-odor

    Liron Rozenkrantz et al.
    Women with unexplained miscarriages have an altered behavioral and brain response to men's body-odor, and this may reflect a factor in their condition.
    1. Stem Cells and Regenerative Medicine

    Lef1 expression in fibroblasts maintains developmental potential in adult skin to regenerate wounds

    Quan M Phan et al.
    Adult wound repair can be rejuvenated to heal like young skin by activating neonatal transcription factors in fibroblasts.
    1. Microbiology and Infectious Disease

    Phenotypic analysis of the unstimulated in vivo HIV CD4 T cell reservoir

    Jason Neidleman et al.
    An in-depth view of the in vivo blood and tissue HIV reservoir is presented highlighting shared phenotypic features between individuals, thus enabling marked ex vivo enrichment of replication-competent latent cells.
    1. Biochemistry and Chemical Biology

    Alkylative damage of mRNA leads to ribosome stalling and rescue by trans translation in bacteria

    Erica N Thomas et al.
    Alkylation stress modify mRNAs and results in translation arrest, which activates the ribosome-rescue pathway of trans translation in bacteria.
    1. Cell Biology
    2. Developmental Biology

    TMEM79/MATTRIN defines a pathway for Frizzled regulation and is required for Xenopus embryogenesis

    Maorong Chen et al.
    TMEM79 targets frizzled receptor for degradation through inhibiting USP8 and is required for Xenopus embryogenesis.
    1. Developmental Biology
    2. Neuroscience

    Enteric glia as a source of neural progenitors in adult zebrafish

    Sarah McCallum et al.
    Characterization of a novel population of enteric nervous system glial cells in zebrafish reveals their proliferative and neurogenic properties under homeostatic conditions in adults, properties difficult to model in mammals.
    1. Neuroscience

    Neural variability determines coding strategies for natural self-motion in macaque monkeys

    Isabelle Mackrous et al.
    Whether central vestibular neurons implement faithful stimulus encoding for the vestibulo-occular reflex or optimized coding via temporal whitening for other vestibular functions is determined by neural variability.
    1. Neuroscience

    Testicular hormones mediate robust sex differences in impulsive choice in rats

    Caesar M Hernandez et al.
    Sex differences in impulsive decision making, such that males are less impulsive than females, are critically dependent upon testicular but not ovarian hormones.

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