In a drug choice setting, rats’ preference is initially driven by deliberative processes but shifts to more automatic selection processes after extended training, in accordance with the sequential choice model.
The orbitofrontal neurons only encode the value of one item, which may be selected by covert attention combining factors of value and visual salience, suggesting a sequential processing mechanism of value information in the brain.
Confronting different models of chromatin accessibility with temporally resolved transcription profiles favors a scenario where transcription factors actively, rather than passively, drive chromatin from the inaccessible to the accessible state.
A data-driven within-host model reveals that different antibiotics are associated with divergent effects on antibiotic resistance carriage and abundance in hospitalised patients, with important implications for antibiotic stewardship.
Error detection is contingent on the continuation of evidence accumulation after choice commitment, and the speed and accuracy of this process are modulated by high-level signals from medial frontal cortex.