80 results found
    1. Neuroscience

    Projections from thalamic nucleus reuniens to hippocampal CA1 area participate in context fear extinction by affecting extinction-induced molecular remodeling of excitatory synapses

    Magdalena Ziółkowska, Narges Sotoudeh ... Kasia Radwanska
    Confocal and electron microscopy analyses reveal that contextual fear extinction induces structural remodeling of thalamic projections to the CA1 area of the hippocampus.
    1. Neuroscience

    Syngap1 regulates the synaptic drive and membrane excitability of Parvalbumin-positive interneurons in mouse auditory cortex

    Ruggiero Francavilla, Bidisha Chattopadhyaya ... Graziella Di Cristo
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
    1. Neuroscience

    A non-conducting role of the Cav1.4 Ca2+ channel drives homeostatic plasticity at the cone photoreceptor synapse

    J Wesley Maddox, Gregory J Ordemann ... Amy Lee
    In congenital stationary night blindness type 2, Cav3 channels may maintain cone synaptic output and visual function provided that the nonconducting role of Cav1.4 in cone synaptogenesis remains intact.
    1. Neuroscience

    Molecular characterization of gustatory second-order neurons reveals integrative mechanisms of gustatory and metabolic information

    Rubén Mollá-Albaladejo, Manuel Jiménez-Caballero, Juan A Sánchez-Alcañiz
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Compelling
    • Incomplete
    1. Neuroscience

    Cone bipolar cell synapses generate transient versus sustained signals in parallel ON pathways of the mouse retina

    Sidney P Kuo, Wan-Qing Yu ... Fred Rieke
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Cell Biology
    2. Neuroscience

    Combining array tomography with electron tomography provides insights into leakiness of the blood-brain barrier in mouse cortex

    Georg Kislinger, Gunar Fabig ... Martina Schifferer
    An array tomography and electron tomography hybrid approach based on coated plastic tape as support advances ultrastructural analysis of biological phenomena that require cell- and tissue-level contextualization of the finest subcellular textures.
    1. Biochemistry and Chemical Biology

    Structural mechanisms for VMAT2 inhibition by tetrabenazine

    Michael P Dalton, Mary Hongying Cheng ... Jonathan A Coleman
    The structure of the vesicular monoamine transporter 2 bound to Huntington’s chorea drug tetrabenazine elucidates mechanisms of inhibition and neurotransmitter transport.
    1. Neuroscience

    Molecular identification of wide-field amacrine cells in mouse retina that encode stimulus orientation

    Silvia J. Park, Wanyu Lei ... Jonathan B. Demb
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Developmental Biology
    2. Neuroscience

    A new look at the architecture and dynamics of the Hydra nerve net

    Athina Keramidioti, Sandra Schneid ... Charles N David
    A novel pan-neuronal antibody has revealed the organization of the nerve net controlling all behavior in the simple cnidarian Hydra.
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    Energetics of the microsporidian polar tube invasion machinery

    Ray Chang, Ari Davydov ... Manu Prakash
    Unraveling the ultrafast polar tube ejection in microsporidia reveals extreme cellular hydraulics, providing a data-driven model for infectious cargo transport, with implications for physical approaches to understanding microsporidia transmission.

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