6 results found
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Science Forum: Viral factors in influenza pandemic risk assessment

    Marc Lipsitch, Wendy Barclay ... Colin A Russell
    We identify key strengths and limitations in use of viral genotyping and phenotyping to estimate pandemic risk from influenza A viruses, focusing on 3 traits, hemagglutinin binding specificity, hemagglutinin pH of activation, and polymerase complex efficiency.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    MERS-CoV spillover at the camel-human interface

    Gytis Dudas, Luiz Max Carvalho ... Trevor Bedford
    MERS-CoV infections in the Arabian Peninsula are the result of several hundred spillover events from viruses circulating in camels into the human population.
    1. Genetics and Genomics

    Characterization of full-length CNBP expanded alleles in myotonic dystrophy type 2 patients by Cas9-mediated enrichment and nanopore sequencing

    Massimiliano Alfano, Luca De Antoni ... Marzia Rossato
    A novel sequencing-based method to characterize CNBP microsatellite expansions in DM2 patients demonstrates benefits for an improved dissection of DM2 genetic architecture, thus potentially ameliorating patient stratification and genetic counseling.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Using paired serology and surveillance data to quantify dengue transmission and control during a large outbreak in Fiji

    Adam J Kucharski, Mike Kama ... Martin L Hibberd
    A combination of surveillance data, paired sera and mathematical modelling reveals which factors may influence dengue transmission and control in island settings.
    1. Epidemiology and Global Health

    Changes in transmission of Enterovirus D68 (EV-D68) in England inferred from seroprevalence data

    Margarita Pons-Salort, Ben Lambert ... Nicholas C Grassly
    Serocatalytic models applied to seroprevalence data from England reveal an increase in Enterovirus D68 transmission that occurred before 2011.
    1. Epidemiology and Global Health

    Enteropathogen antibody dynamics and force of infection among children in low-resource settings

    Benjamin F Arnold, Diana L Martin ... Jeffrey W Priest
    Among children in low-resource settings, diverse enteropathogens share common, population-level antibody dynamics, which creates a new opportunity to estimate transmission through serologic surveillance.

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