1,349 results found
    1. Computational and Systems Biology

    Research: Bias in the reporting of sex and age in biomedical research on mouse models

    Oscar Flórez-Vargas, Andy Brass ... Goran Nenadic
    A text-mining study suggests that about half of the papers reporting the results of experiments on mice do not report the sex and age of the mice.
  1. Science Forum: Sex differences and sex bias in human circadian and sleep physiology research

    Manuel Spitschan, Nayantara Santhi ... Rhiannon White
    Research on human sleep and circadian physiology exhibits a bias towards male subjects, creating a sex data gap which holds potential real-world impact and requires concerted effort to close.
    1. Evolutionary Biology
    2. Genetics and Genomics

    The genomic footprint of social stratification in admixing American populations

    Alex Mas-Sandoval, Sara Mathieson, Matteo Fumagalli
    Social hierarchies resulting from the European colonization of the Americas stratified the population structure, leading to ancestry-related assortative mating and sex bias patterns that can be inferred from the genomes of the populations across the continent.
    1. Chromosomes and Gene Expression
    2. Evolutionary Biology

    High rates of evolution preceded shifts to sex-biased gene expression in Leucadendron, the most sexually dimorphic angiosperms

    Mathias Scharmann, Anthony G Rebelo, John R Pannell
    In the dioecious plant genus Leucadendron, shifts to sex-biased gene expression occurred predominantly in genes with ancestrally high rates of expression evolution, and were not correlated with morphology.
    1. Epidemiology and Global Health

    Longitudinal trajectories, correlations and mortality associations of nine biological ages across 20-years follow-up

    Xia Li, Alexander Ploner ... Sara Hägg
    Biological ages have the potential to provide aging-related information beyond chronological age and can be predictive of mortality independently of both chronological age and different types of biological ages.
    1. Cell Biology
    2. Developmental Biology

    Sex determination gene transformer regulates the male-female difference in Drosophila fat storage via the adipokinetic hormone pathway

    Lianna W Wat, Zahid S Chowdhury ... Elizabeth J Rideout
    Drosophila females store more fat than males because the presence of a functional Transformer protein in females limits adipokinetic hormone production and pathway activity.
  2. Meta-Research: A 10-year follow-up study of sex inclusion in the biological sciences

    Nicole C Woitowich, Annaliese Beery, Teresa Woodruff
    Sex-inclusive research practices have increased in many biological disciplines over the past decade, yet critical sex-based analyses and reporting have remained stagnant in most of these disciplines.
    1. Evolutionary Biology
    2. Genetics and Genomics

    A paternal bias in germline mutation is widespread in amniotes and can arise independently of cell division numbers

    Marc de Manuel, Felix L Wu, Molly Przeworski
    A paternal bias in germline mutation is seen throughout amniotes and may be explained by sex differences in DNA damage and repair after primordial germ cell specification.
    1. Neuroscience

    Young domestic chicks spontaneously represent the absence of objects

    Eszter Szabó, Cinzia Chiandetti ... Giorgio Vallortigara
    Without specific training, young chicks represent the absence of objects, showing that the concept of 'nothing' is available to nonhuman animals and does not require linguistic tools, such as negation.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Sex-based differences in clearance of chronic Plasmodium falciparum infection

    Jessica Briggs, Noam Teyssier ... Bryan Greenhouse
    Lower malaria prevalence in females does not appear to be due to lower rates of infection but rather due to faster clearance of asymptomatic infections.

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