Within 100 generations after an environmental shift in an evolution experiment, rapid sex-specific adaptation occurred, which is potentially facilitated by selection on standing variation in sex-specific genetic architecture.
Development and application of highly sensitive in situ transcriptomics method, Flura-seq, in identifying dynamic organ-specific transcriptomes in early stage breast cancer metastasis have been described.
Social dominance has opposing effects on behavior following stress in male vs. female mice indicating an important role in sex differences in the stress response.
Motor neurons adjust their sensitivity to direction of movement in a manner analogous to how neurons in the visual system adjust their sensitivity to light.
Combining in silico and experimental approaches to identify and understand the residue changes in the H-NS protein that allowed bacteria to adapt environment-sensing to different habitats.
Hierarchical modeling of internalizing symptoms and task performance reveals that difficulty adapting probabilistic learning to second-order uncertainty is common to anxiety and depression and holds across rewarding and punishing outcomes.
Single-cell FRET measurements reveal large temporal activity fluctuations within this signaling pathway in Escherichia coli, caused by stochasticity of receptor methylation combined with allosteric interactions and slow rearrangements within receptor clusters.
The first genomic view of beetle luciferase evolution indicates evolutionary independence of luciferase between fireflies and click-beetles, and provide valuable datasets which will accelerate the discovery of new biotechnological tools.
