Browse the search results

Page 2 of 93
    1. Cell Biology
    2. Developmental Biology

    Banp regulates DNA damage response and chromosome segregation during the cell cycle in zebrafish retina

    Swathy Babu, Yuki Takeuchi, Ichiro Masai
    Banp is a transcription activator of cell cycle genes like cenpt, ncapg, and wrnip1 to prevent genotoxic stress during rapid cell division and its repercussions on development and disease.
    1. Epidemiology and Global Health
    2. Genetics and Genomics

    Taller height and risk of coronary heart disease and cancer: A within-sibship Mendelian randomization study

    Laurence J Howe, Ben Brumpton ... Neil M Davies
    Genetic data from siblings provides strong evidence that taller height increases the risk of cancers but lowers the risk of coronary disease.
    1. Genetics and Genomics
    2. Neuroscience

    Genetic Chimerism: Marmosets contain multitudes

    Kenneth Chiou, Noah Snyder-Mackler
    Single-cell RNA sequencing reveals the extent to which marmosets carry genetically distinct cells from their siblings.
    Version of Record
    Insight
    1. Evolutionary Biology
    2. Genetics and Genomics

    Reduced signal for polygenic adaptation of height in UK Biobank

    Jeremy J Berg, Arbel Harpak ... Graham Coop
    Many prior signals of polygenic adaptation on human height do not replicate in the UK Biobank.
    1. Developmental Biology

    Emx2 regulates hair cell rearrangement but not positional identity within neuromasts

    Sho Ohta, Young Rae Ji ... Doris K Wu
    Emx2 is not required for sibling HCs to acquire their designated locations within the neuromast, inferring that Emx2 mediates opposite HC orientation by changing location of hair bundle establishment.
    1. Neuroscience

    The CNS connectome of a tadpole larva of Ciona intestinalis (L.) highlights sidedness in the brain of a chordate sibling

    Kerrianne Ryan, Zhiyuan Lu, Ian A Meinertzhagen
    Serial-section EM analysis uncovers the CNS connectome of a Ciona larva, the second of any entire nervous system, and exposes left-right asymmetries in its synaptic circuits.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    The origins and relatedness structure of mixed infections vary with local prevalence of P. falciparum malaria

    Sha Joe Zhu, Jason A Hendry ... Gil McVean
    Variation in the rate of mixed infections by malaria parasites and the relatedness structure among infecting strains reveals diversity in local epidemiological processes.
    1. Chromosomes and Gene Expression
    2. Microbiology and Infectious Disease

    GUY1 confers complete female lethality and is a strong candidate for a male-determining factor in Anopheles stephensi

    Frank Criscione, Yumin Qi, Zhijian Tu
    Evidence that the small GUY1 protein is a strong candidate for being a male-determining factor is provided via the establishment of Guy1 transgenic lines of mosquitoes that confer complete and stable female lethality.
    1. Genetics and Genomics

    Large, three-generation human families reveal post-zygotic mosaicism and variability in germline mutation accumulation

    Thomas A Sasani, Brent S Pedersen ... Aaron R Quinlan
    Rates of germline mutation accumulation are highly variable across families of similar genetic ancestry, and post-zygotic mosaicism is a substantial source of de novo mutations.